Adult‐onset cyclic bicytopenia: A case report and review of treatment of cyclic hematopoiesis

Ayalew Tefferi, Lawrence A. Solberg, Robert M. Petitt, Larry G. Willis

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

A unique case of adult‐onset synchronous cyclic neutropenia and thrombocytopenia occurring at six‐week intervals is presented. Periods of cytopenia were associated with fever, myalgias, gastrointestinal symptoms, and mild mucocutaneous bleeding. Alternate‐day steroid treatment failed to correct the periodic fluctuations in peripheral blood counts but ameliorated symptoms during cytopenia. The treatment of cyclic hematopoiesis is reviewed.

Original languageEnglish (US)
Pages (from-to)181-185
Number of pages5
JournalAmerican journal of hematology
Volume30
Issue number3
DOIs
StatePublished - Mar 1989

Keywords

  • cyclic bicytopenia
  • cyclic nematopoiesis
  • treatment

ASJC Scopus subject areas

  • Hematology

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