Adult respiratory distress syndrome associated with antiphospholipid antibody syndrome

S. Ghosh, H. D. Walters, J. H. Joist, T. G. Osborn, T. L. Moore

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

Antiphospholipid antibody syndrome (APS) has been shown to be associated with arterial and venous thromboses, recurrent miscarriages, and thrombocytopenia. We describe 3 cases of adult respiratory distress syndrome (ARDS) in patients with primary APS. The autopsy in one patient revealed no evidence of vasculitis, but extensive small vessel thrombosis of multiple organs including the lungs was seen. No infectious process, connective tissue diseases, or pulmonary edema could be documented and there was no clinical or laboratory evidence of vasculitis in the other 2 patients. The 2 patients who survived responded dramatically to intravenous steroids.

Original languageEnglish (US)
Pages (from-to)1406-1408
Number of pages3
JournalJournal of Rheumatology
Volume20
Issue number8
StatePublished - Oct 12 1993

Keywords

  • ADULT RESPIRATORY DISTRESS SYNDROME
  • PRIMARY ANTIPHOSPHOLIPID ANTIBODY SYNDROME

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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