Adrenomedullin: An autocrine/paracrine factor for cardiorenal protection

Toshihiro Tsuruda; John C. Burnett

doi:10.1161/01.RES.0000015462.11528.28

Adrenomedullin: An autocrine/paracrine factor for cardiorenal protection

Toshihiro Tsuruda, John C. Burnett

Cardiovascular Medicine

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

In summary, the study by Nishimatsu and coworkers advances our understanding of the biology of endogenous AM and supports the role of endogenous AM as an autocrine or paracrine factor in cardiorenal regulation. Furthermore, endogenous AM contributes a cytoprotective effect against organ damage, indicating that AM is a potential therapeutic candidate for the treatment of cardiovascular and renal disease.

Original language	English (US)
Pages (from-to)	625-627
Number of pages	3
Journal	Circulation research
Volume	90
Issue number	6
DOIs	https://doi.org/10.1161/01.RES.0000015462.11528.28
State	Published - Apr 5 2002

Keywords

Adrenomedullin
Autocrine
Knockout
Paracrine
Transgenic

ASJC Scopus subject areas

Physiology
Cardiology and Cardiovascular Medicine

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10.1161/01.RES.0000015462.11528.28

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abstract = "In summary, the study by Nishimatsu and coworkers advances our understanding of the biology of endogenous AM and supports the role of endogenous AM as an autocrine or paracrine factor in cardiorenal regulation. Furthermore, endogenous AM contributes a cytoprotective effect against organ damage, indicating that AM is a potential therapeutic candidate for the treatment of cardiovascular and renal disease.",

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AB - In summary, the study by Nishimatsu and coworkers advances our understanding of the biology of endogenous AM and supports the role of endogenous AM as an autocrine or paracrine factor in cardiorenal regulation. Furthermore, endogenous AM contributes a cytoprotective effect against organ damage, indicating that AM is a potential therapeutic candidate for the treatment of cardiovascular and renal disease.

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KW - Autocrine

KW - Knockout

KW - Paracrine

KW - Transgenic

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Adrenomedullin: An autocrine/paracrine factor for cardiorenal protection

Abstract

Keywords

ASJC Scopus subject areas

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