TY - JOUR
T1 - Adrenocortical carcinoma metastatic to the orbit
AU - Bartley, George B.
AU - Campbell, R. Jean
AU - Salomão, Diva R.
AU - Bradley, Elizabeth A.
AU - Marsh, W. Richard
AU - Bite, Uldis
PY - 2001/5
Y1 - 2001/5
N2 - Purpose: To describe the clinical course and histopathologic features of a patient with adrenocortical carcinoma metastatic to the orbit. Methods: Case report and literature review. Results: A 24-year-old man first came to medical attention because of symptoms referable to a 4.47-kg, nonfunctioning carcinoma of the left adrenal cortex. Several metastases ensued, including a large tumor to the right superior lateral bony orbit with extension to the brain, temporalis fossa, and orbit proper. The tumor was resected with the use of a combined neurosurgical, ophthalmic, and craniofacial approach. The patient died of widespread metastatic disease 15 months after the orbital operation. Conclusions: Metastasis to the orbit from adrenocortical carcinoma is rare. Surgical resection is the treatment of choice, with adjunctive radiation therapy and chemotherapy in some cases. The prognosis is poor.
AB - Purpose: To describe the clinical course and histopathologic features of a patient with adrenocortical carcinoma metastatic to the orbit. Methods: Case report and literature review. Results: A 24-year-old man first came to medical attention because of symptoms referable to a 4.47-kg, nonfunctioning carcinoma of the left adrenal cortex. Several metastases ensued, including a large tumor to the right superior lateral bony orbit with extension to the brain, temporalis fossa, and orbit proper. The tumor was resected with the use of a combined neurosurgical, ophthalmic, and craniofacial approach. The patient died of widespread metastatic disease 15 months after the orbital operation. Conclusions: Metastasis to the orbit from adrenocortical carcinoma is rare. Surgical resection is the treatment of choice, with adjunctive radiation therapy and chemotherapy in some cases. The prognosis is poor.
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U2 - 10.1097/00002341-200105000-00012
DO - 10.1097/00002341-200105000-00012
M3 - Article
C2 - 11388389
AN - SCOPUS:0035000137
SN - 0740-9303
VL - 17
SP - 215
EP - 220
JO - Ophthalmic Plastic and Reconstructive Surgery
JF - Ophthalmic Plastic and Reconstructive Surgery
IS - 3
ER -