Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis

George R. Thompson, Janis E. Blair, Sharon Wang, Robert Bercovitch, Michael Bolaris, Dane Van Den Akker, Rodrigo Lopez, Arash Heidari, Antonino Catanzaro, Jose Cadena, Peter Chin-Hong, Brad Spellberg, Royce Johnson

Research output: Contribution to journal › Article

6 Citations (Scopus)

Abstract

Coccidioidal meningitis (CM) has high morbidity, and adjunctive measures to improve outcomes are needed. Using an established multicenter retrospective cohort study of CM (N = 221), we found that patients receiving adjunctive corticosteroids had a significant reduction in secondary cerebrovascular events (P =.0049). Those with CM-associated cerebrovascular events (8%) may benefit from short-term corticosteroids.

Original languageEnglish (US)
Pages (from-to)338-341
Number of pages4
JournalClinical Infectious Diseases
Volume65
Issue number2
DOIs
StatePublished - Jul 15 2017

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Meningitis
Adrenal Cortex Hormones
Cohort Studies
Therapeutics
Retrospective Studies
Morbidity

Keywords

  • coccidioidomycosis
  • corticosteroids
  • meningitis
  • stroke.
  • vasculitis

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Thompson, G. R., Blair, J. E., Wang, S., Bercovitch, R., Bolaris, M., Van Den Akker, D., ... Johnson, R. (2017). Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis. Clinical Infectious Diseases, 65(2), 338-341. https://doi.org/10.1093/cid/cix318

Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis. / Thompson, George R.; Blair, Janis E.; Wang, Sharon; Bercovitch, Robert; Bolaris, Michael; Van Den Akker, Dane; Lopez, Rodrigo; Heidari, Arash; Catanzaro, Antonino; Cadena, Jose; Chin-Hong, Peter; Spellberg, Brad; Johnson, Royce.

In: Clinical Infectious Diseases, Vol. 65, No. 2, 15.07.2017, p. 338-341.

Research output: Contribution to journal › Article

Thompson, GR, Blair, JE, Wang, S, Bercovitch, R, Bolaris, M, Van Den Akker, D, Lopez, R, Heidari, A, Catanzaro, A, Cadena, J, Chin-Hong, P, Spellberg, B & Johnson, R 2017, 'Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis', Clinical Infectious Diseases, vol. 65, no. 2, pp. 338-341. https://doi.org/10.1093/cid/cix318
Thompson GR, Blair JE, Wang S, Bercovitch R, Bolaris M, Van Den Akker D et al. Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis. Clinical Infectious Diseases. 2017 Jul 15;65(2):338-341. https://doi.org/10.1093/cid/cix318
Thompson, George R. ; Blair, Janis E. ; Wang, Sharon ; Bercovitch, Robert ; Bolaris, Michael ; Van Den Akker, Dane ; Lopez, Rodrigo ; Heidari, Arash ; Catanzaro, Antonino ; Cadena, Jose ; Chin-Hong, Peter ; Spellberg, Brad ; Johnson, Royce. / Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis. In: Clinical Infectious Diseases. 2017 ; Vol. 65, No. 2. pp. 338-341.
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