Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis

George R. Thompson; Janis E. Blair; Sharon Wang; Robert Bercovitch; Michael Bolaris; Dane Van Den Akker; Rodrigo Lopez; Arash Heidari; Antonino Catanzaro; Jose Cadena; Peter Chin-Hong; Brad Spellberg; Royce Johnson

doi:10.1093/cid/cix318

Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis

George R. Thompson, Janis E. Blair, Sharon Wang, Robert Bercovitch, Michael Bolaris, Dane Van Den Akker, Rodrigo Lopez, Arash Heidari, Antonino Catanzaro, Jose Cadena, Peter Chin-Hong, Brad Spellberg, Royce Johnson

Infectious Diseases

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Coccidioidal meningitis (CM) has high morbidity, and adjunctive measures to improve outcomes are needed. Using an established multicenter retrospective cohort study of CM (N = 221), we found that patients receiving adjunctive corticosteroids had a significant reduction in secondary cerebrovascular events (P =.0049). Those with CM-associated cerebrovascular events (8%) may benefit from short-term corticosteroids.

Original language	English (US)
Pages (from-to)	338-341
Number of pages	4
Journal	Clinical Infectious Diseases
Volume	65
Issue number	2
DOIs	https://doi.org/10.1093/cid/cix318
State	Published - Jul 15 2017

Keywords

coccidioidomycosis
corticosteroids
meningitis
stroke.
vasculitis

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1093/cid/cix318

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abstract = "Coccidioidal meningitis (CM) has high morbidity, and adjunctive measures to improve outcomes are needed. Using an established multicenter retrospective cohort study of CM (N = 221), we found that patients receiving adjunctive corticosteroids had a significant reduction in secondary cerebrovascular events (P =.0049). Those with CM-associated cerebrovascular events (8%) may benefit from short-term corticosteroids.",

keywords = "coccidioidomycosis, corticosteroids, meningitis, stroke., vasculitis",

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AU - Thompson, George R.

AU - Blair, Janis E.

AU - Wang, Sharon

AU - Bercovitch, Robert

AU - Bolaris, Michael

AU - Van Den Akker, Dane

AU - Lopez, Rodrigo

AU - Heidari, Arash

AU - Catanzaro, Antonino

AU - Cadena, Jose

AU - Chin-Hong, Peter

AU - Spellberg, Brad

AU - Johnson, Royce

PY - 2017/7/15

Y1 - 2017/7/15

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AB - Coccidioidal meningitis (CM) has high morbidity, and adjunctive measures to improve outcomes are needed. Using an established multicenter retrospective cohort study of CM (N = 221), we found that patients receiving adjunctive corticosteroids had a significant reduction in secondary cerebrovascular events (P =.0049). Those with CM-associated cerebrovascular events (8%) may benefit from short-term corticosteroids.

KW - coccidioidomycosis

KW - corticosteroids

KW - meningitis

KW - stroke.

KW - vasculitis

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Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis

Abstract

Keywords

ASJC Scopus subject areas

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