Adherence to a pedometer-based physical activity intervention following kidney transplant and impact on metabolic parameters

Elizabeth C. Lorenz, Hatem Amer, Patrick G. Dean, Mark D Stegall, Fernando G Cosio, Andrea L Cheville

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

The majority of kidney transplant recipients die from cardiovascular events. Physical activity may be a modifiable risk factor for cardiovascular disease following transplant. The goal of our study was to examine adherence to a physical activity intervention following kidney transplant and its impact on metabolic parameters. All patients who received a kidney transplant at our center between 12/2010 and 12/2011 received usual care (n = 162), while patients transplanted between 12/2011 and 1/2013 received a 90-day pedometer-based physical activity intervention (n = 145). Metabolic parameters were assessed at four and 12 months post-transplant. Baseline demographics and clinical management were similar between cohorts. Adherence to the prescription was 36.5%. Patients in the physical activity cohort had lower systolic and diastolic blood pressure four months post-transplant compared to the usual care cohort (122 ± 18 vs. 126 ± 16 mmHg, p = 0.049 and 73 ± 10 vs. 77 ± 9, p = 0.004) and less impaired fasting glucose (20.7% vs. 30.9%, p = 0.04). Twelve-month outcomes were not different between cohorts. Over one-third of our cohort adhered to a pedometer-based physical activity intervention following kidney transplant, and the intervention was associated with improved metabolic parameters. Further study of post-transplant exercise interventions and methods to optimize long-term adherence are needed.

Original languageEnglish (US)
Pages (from-to)560-568
Number of pages9
JournalClinical Transplantation
Volume29
Issue number6
DOIs
StatePublished - Jun 1 2015

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Keywords

  • Blood pressure
  • Cardiovascular disease
  • Exercise
  • Kidney transplant
  • Metabolic outcomes

ASJC Scopus subject areas

  • Transplantation

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