Adherence to a pedometer-based physical activity intervention following kidney transplant and impact on metabolic parameters

Elizabeth C. Lorenz, Hatem Amer, Patrick G. Dean, Mark D. Stegall, Fernando G. Cosio, Andrea L. Cheville

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

The majority of kidney transplant recipients die from cardiovascular events. Physical activity may be a modifiable risk factor for cardiovascular disease following transplant. The goal of our study was to examine adherence to a physical activity intervention following kidney transplant and its impact on metabolic parameters. All patients who received a kidney transplant at our center between 12/2010 and 12/2011 received usual care (n = 162), while patients transplanted between 12/2011 and 1/2013 received a 90-day pedometer-based physical activity intervention (n = 145). Metabolic parameters were assessed at four and 12 months post-transplant. Baseline demographics and clinical management were similar between cohorts. Adherence to the prescription was 36.5%. Patients in the physical activity cohort had lower systolic and diastolic blood pressure four months post-transplant compared to the usual care cohort (122 ± 18 vs. 126 ± 16 mmHg, p = 0.049 and 73 ± 10 vs. 77 ± 9, p = 0.004) and less impaired fasting glucose (20.7% vs. 30.9%, p = 0.04). Twelve-month outcomes were not different between cohorts. Over one-third of our cohort adhered to a pedometer-based physical activity intervention following kidney transplant, and the intervention was associated with improved metabolic parameters. Further study of post-transplant exercise interventions and methods to optimize long-term adherence are needed.

Original languageEnglish (US)
Pages (from-to)560-568
Number of pages9
JournalClinical Transplantation
Volume29
Issue number6
DOIs
StatePublished - Jun 1 2015

Keywords

  • Blood pressure
  • Cardiovascular disease
  • Exercise
  • Kidney transplant
  • Metabolic outcomes

ASJC Scopus subject areas

  • Transplantation

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