Adenoviruses for vaccination

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Adenoviruses (Ads) are arguably one of the most potent vectors for in vivo gene delivery. They are also thought to be one of the most immunogenic vectors driving potent cellular and humoral immune responses. While this immunogenicity can be a handicap in using Ads for gene therapy, this feature can be a potent strength when Ads are instead used as gene-based vaccine. This chapter discussed this application area for Ad vectors.

Original languageEnglish (US)
Title of host publicationTherapeutic Applications of Adenoviruses
PublisherCRC Press
Pages185-209
Number of pages25
ISBN (Electronic)9781498745499
ISBN (Print)9781498745482
DOIs
StatePublished - Dec 12 2016

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Barry, M. A. (2016). Adenoviruses for vaccination. In Therapeutic Applications of Adenoviruses (pp. 185-209). CRC Press. https://doi.org/10.1201/9781315368832