Adenovirally delivered enzyme prodrug therapy with herpes simplex virus-thymidine kinase in composite tissue free flaps shows therapeutic efficacy in rat models of glioma

Rohit Seth, Aadil A. Khan, Timothy D. Pencavel, Michelle J. Wilkinson, Joan N. Kyula, Guy Simpson, Hardev Pandha, Alan Melcher, Richard Vile, Paul A. Harris, Kevin J. Harrington

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Medicine & Life Sciences