TY - JOUR
T1 - Acute systemic immune activation following conjunctival exposure to staphylococcal enterotoxin B
AU - Rajagopalan, Govindarajan
AU - Smart, Michele K.
AU - Patel, Robin
AU - David, Chella S.
PY - 2006/10
Y1 - 2006/10
N2 - Conjunctival exposure to the Staphylococcus aureus superantigen staphylococcal enterotoxin B (SEB) may occur accidentally, as a result of bioterrorism, or during colonization or infection of the external eye. Using human leukocyte antigen class II transgenic mice, we show for the first time that conjunctival exposure to SEB can cause robust systemic immune activation.
AB - Conjunctival exposure to the Staphylococcus aureus superantigen staphylococcal enterotoxin B (SEB) may occur accidentally, as a result of bioterrorism, or during colonization or infection of the external eye. Using human leukocyte antigen class II transgenic mice, we show for the first time that conjunctival exposure to SEB can cause robust systemic immune activation.
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U2 - 10.1128/IAI.00671-06
DO - 10.1128/IAI.00671-06
M3 - Article
C2 - 16988282
AN - SCOPUS:33749267789
SN - 0019-9567
VL - 74
SP - 6016
EP - 6019
JO - Infection and Immunity
JF - Infection and Immunity
IS - 10
ER -