Acute Renal Infarction Due to Fungal Vascular Invasion in Disseminated Candidiasis

Shawn M. McGee; Carrie A. Thompson; Candace F. Granberg; Joel C. Hutcheson; David R. Vandersteen; Yuri Reinberg; James J. Wolpert

doi:10.1016/j.urology.2008.08.429

Acute Renal Infarction Due to Fungal Vascular Invasion in Disseminated Candidiasis

Shawn M. McGee, Carrie A. Thompson, Candace F. Granberg, Joel C. Hutcheson, David R. Vandersteen, Yuri Reinberg, James J. Wolpert

Hematology

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Disseminated candidiasis occurs almost exclusively in leukemic patients recovering from neutropenia. Although renal involvement can be a sequela of disseminated candidiasis, acute renal infarction secondary to Candida invading the renal vasculature has not previously been reported. Our patient, who was being treated for acute myelogenous leukemia, developed complete obstruction of the right renal vessels during the course of 36 hours as documented by serial renal ultrasound scans with Doppler investigation of the vasculature. Histopathologic examination of the nephrectomy specimen revealed complete infarction of the kidney secondary to Candida spp. infiltrating the parenchyma and occluding the hilar vessels.

Original language	English (US)
Pages (from-to)	535-537
Number of pages	3
Journal	Urology
Volume	73
Issue number	3
DOIs	https://doi.org/10.1016/j.urology.2008.08.429
State	Published - Mar 1 2009

ASJC Scopus subject areas

Urology

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title = "Acute Renal Infarction Due to Fungal Vascular Invasion in Disseminated Candidiasis",

abstract = "Disseminated candidiasis occurs almost exclusively in leukemic patients recovering from neutropenia. Although renal involvement can be a sequela of disseminated candidiasis, acute renal infarction secondary to Candida invading the renal vasculature has not previously been reported. Our patient, who was being treated for acute myelogenous leukemia, developed complete obstruction of the right renal vessels during the course of 36 hours as documented by serial renal ultrasound scans with Doppler investigation of the vasculature. Histopathologic examination of the nephrectomy specimen revealed complete infarction of the kidney secondary to Candida spp. infiltrating the parenchyma and occluding the hilar vessels.",

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AU - McGee, Shawn M.

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AU - Granberg, Candace F.

AU - Hutcheson, Joel C.

AU - Vandersteen, David R.

AU - Reinberg, Yuri

AU - Wolpert, James J.

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AB - Disseminated candidiasis occurs almost exclusively in leukemic patients recovering from neutropenia. Although renal involvement can be a sequela of disseminated candidiasis, acute renal infarction secondary to Candida invading the renal vasculature has not previously been reported. Our patient, who was being treated for acute myelogenous leukemia, developed complete obstruction of the right renal vessels during the course of 36 hours as documented by serial renal ultrasound scans with Doppler investigation of the vasculature. Histopathologic examination of the nephrectomy specimen revealed complete infarction of the kidney secondary to Candida spp. infiltrating the parenchyma and occluding the hilar vessels.

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