Abstract
Acute-on-chronic liver failure (ACLF) has recently received more recognition. It is a condition characterized by acute clinical deterioration in patients with chronic liver disease and is often associated with a precipitant event. It is a form of decompensated cirrhosis characterized by the presence of extrahepatic organ failure and high short-term mortality. Several definitions have been recently proposed for ACLF; however, larger prospective studies are still needed to refine our understanding of this new entity. This article explores the most recently proposed definitions, classification, and prognostic models of ACLF.
Original language | English (US) |
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Pages (from-to) | 40-45 |
Number of pages | 6 |
Journal | Current Hepatitis Reports |
Volume | 14 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1 2015 |
Keywords
- Cirrhosis
- Hepatic decompensation
- Liver failure
- Multiorgan failure
ASJC Scopus subject areas
- Hepatology
- Virology