Acute lung injury

Prevention may be the best medicine

John M. Litell, Michelle Ng Gong, Daniel Talmor, Ognjen Gajic

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Acute lung injury affects a subset of hospitalized patients but is not universal. This syndrome can substantially delay ventilator liberation, prolong intensive care unit (ICU) stay, and increase mortality. As with many critical illness syndromes, the available treatment options are limited in number and impact. Once a patient develops lung injury, the best known strategy is supportive care. Observational studies have identified potential risk factors and have suggested that the use and timing of certain critical care interventions may influence the likelihood of developing lung injury. These findings suggest that a well designed screening tool and the systematic application of best practices in critical care may limit the risk of lung injury. An effective prediction score may also facilitate enrollment in pharmacopreventive trials. Development of such tools is accelerated by multicenter collaboration.

Original languageEnglish (US)
Pages (from-to)1546-1554
Number of pages9
JournalRespiratory Care
Volume56
Issue number10
DOIs
StatePublished - Oct 2011

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Acute Lung Injury
Lung Injury
Medicine
Critical Care
Mechanical Ventilators
Practice Guidelines
Critical Illness
Observational Studies
Intensive Care Units
Mortality
Therapeutics

Keywords

  • Acute lung injury
  • Critical illness
  • Intensive care
  • Mechanical ventilation
  • Prevention

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine

Cite this

Acute lung injury : Prevention may be the best medicine. / Litell, John M.; Gong, Michelle Ng; Talmor, Daniel; Gajic, Ognjen.

In: Respiratory Care, Vol. 56, No. 10, 10.2011, p. 1546-1554.

Research output: Contribution to journalArticle

Litell, John M. ; Gong, Michelle Ng ; Talmor, Daniel ; Gajic, Ognjen. / Acute lung injury : Prevention may be the best medicine. In: Respiratory Care. 2011 ; Vol. 56, No. 10. pp. 1546-1554.
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