Acute glomerulonephritis presenting with PRES: A report of 4 cases

Elaine C Wirrell, L. D. Hamiwka, L. A. Hamiwka, S. Grisaru, X. Wei

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Objective: Posterior reversible encephalopathy syndrome (PRES) occurs most commonly in the setting of known hypertension or use of immunosuppressive agents. Design and Methods: We report four previously-well children who presented acutely with altered mentation, seizures and visual disturbances and were diagnosed with PRES. Results: Only one child had a history of gross hematuria prior to the seizure. All four were discovered to be hypertensive only after onset of their neurological symptoms, and were subsequently diagnosed with glomerulonephritis. All four had rapid resolution of neurological symptoms with adequate treatment of hypertension. Conclusions: Blood pressure must be measured promptly in all children presenting with these symptoms. If elevated, the diagnosis of PRES should be strongly considered and a workup for renal disease pursued.

Original languageEnglish (US)
Pages (from-to)316-321
Number of pages6
JournalCanadian Journal of Neurological Sciences
Volume34
Issue number3
StatePublished - Aug 2007
Externally publishedYes

Fingerprint

Posterior Leukoencephalopathy Syndrome
Glomerulonephritis
Seizures
Hypertension
Hematuria
Immunosuppressive Agents
Blood Pressure
Kidney
Therapeutics

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Wirrell, E. C., Hamiwka, L. D., Hamiwka, L. A., Grisaru, S., & Wei, X. (2007). Acute glomerulonephritis presenting with PRES: A report of 4 cases. Canadian Journal of Neurological Sciences, 34(3), 316-321.

Acute glomerulonephritis presenting with PRES : A report of 4 cases. / Wirrell, Elaine C; Hamiwka, L. D.; Hamiwka, L. A.; Grisaru, S.; Wei, X.

In: Canadian Journal of Neurological Sciences, Vol. 34, No. 3, 08.2007, p. 316-321.

Research output: Contribution to journalArticle

Wirrell, EC, Hamiwka, LD, Hamiwka, LA, Grisaru, S & Wei, X 2007, 'Acute glomerulonephritis presenting with PRES: A report of 4 cases', Canadian Journal of Neurological Sciences, vol. 34, no. 3, pp. 316-321.
Wirrell, Elaine C ; Hamiwka, L. D. ; Hamiwka, L. A. ; Grisaru, S. ; Wei, X. / Acute glomerulonephritis presenting with PRES : A report of 4 cases. In: Canadian Journal of Neurological Sciences. 2007 ; Vol. 34, No. 3. pp. 316-321.
@article{b12d13adc39f4329a873455c78bc63bb,
title = "Acute glomerulonephritis presenting with PRES: A report of 4 cases",
abstract = "Objective: Posterior reversible encephalopathy syndrome (PRES) occurs most commonly in the setting of known hypertension or use of immunosuppressive agents. Design and Methods: We report four previously-well children who presented acutely with altered mentation, seizures and visual disturbances and were diagnosed with PRES. Results: Only one child had a history of gross hematuria prior to the seizure. All four were discovered to be hypertensive only after onset of their neurological symptoms, and were subsequently diagnosed with glomerulonephritis. All four had rapid resolution of neurological symptoms with adequate treatment of hypertension. Conclusions: Blood pressure must be measured promptly in all children presenting with these symptoms. If elevated, the diagnosis of PRES should be strongly considered and a workup for renal disease pursued.",
author = "Wirrell, {Elaine C} and Hamiwka, {L. D.} and Hamiwka, {L. A.} and S. Grisaru and X. Wei",
year = "2007",
month = "8",
language = "English (US)",
volume = "34",
pages = "316--321",
journal = "Canadian Journal of Neurological Sciences",
issn = "0317-1671",
publisher = "Canadian Journal of Neurological Sciences",
number = "3",

}

TY - JOUR

T1 - Acute glomerulonephritis presenting with PRES

T2 - A report of 4 cases

AU - Wirrell, Elaine C

AU - Hamiwka, L. D.

AU - Hamiwka, L. A.

AU - Grisaru, S.

AU - Wei, X.

PY - 2007/8

Y1 - 2007/8

N2 - Objective: Posterior reversible encephalopathy syndrome (PRES) occurs most commonly in the setting of known hypertension or use of immunosuppressive agents. Design and Methods: We report four previously-well children who presented acutely with altered mentation, seizures and visual disturbances and were diagnosed with PRES. Results: Only one child had a history of gross hematuria prior to the seizure. All four were discovered to be hypertensive only after onset of their neurological symptoms, and were subsequently diagnosed with glomerulonephritis. All four had rapid resolution of neurological symptoms with adequate treatment of hypertension. Conclusions: Blood pressure must be measured promptly in all children presenting with these symptoms. If elevated, the diagnosis of PRES should be strongly considered and a workup for renal disease pursued.

AB - Objective: Posterior reversible encephalopathy syndrome (PRES) occurs most commonly in the setting of known hypertension or use of immunosuppressive agents. Design and Methods: We report four previously-well children who presented acutely with altered mentation, seizures and visual disturbances and were diagnosed with PRES. Results: Only one child had a history of gross hematuria prior to the seizure. All four were discovered to be hypertensive only after onset of their neurological symptoms, and were subsequently diagnosed with glomerulonephritis. All four had rapid resolution of neurological symptoms with adequate treatment of hypertension. Conclusions: Blood pressure must be measured promptly in all children presenting with these symptoms. If elevated, the diagnosis of PRES should be strongly considered and a workup for renal disease pursued.

UR - http://www.scopus.com/inward/record.url?scp=34548392165&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34548392165&partnerID=8YFLogxK

M3 - Article

C2 - 17803029

AN - SCOPUS:34548392165

VL - 34

SP - 316

EP - 321

JO - Canadian Journal of Neurological Sciences

JF - Canadian Journal of Neurological Sciences

SN - 0317-1671

IS - 3

ER -