Acute Gastrointestinal Bleeding from Portal Hypertensive Gastropathy: Prevalence and Clinical Features

Christopher J. Gostout, Thomas R. Viggiano, Rita K. Balm

Research output: Contribution to journalArticle

67 Scopus citations


The clinical and endoscopic features of patients diagnosed with acute bleeding due to portal hypertensive gastropathv (PHG) were evaluated. Acute bleeding from PHG was diagnosed in 12 patients (O.8%) of 1496 patient admissions prospectively evaluated by our Gastrointestinal Bleeding Team over a 3‐yr period, and accounted for 87% of nonvariceal bleeding diagnosed in patients with liver disease. The median age of PHG patients (8M:4F) was 66 yr (range, 37–72). The most common underlying liver disease was alcoholic cirrhosis (five patients). The majority of patients presented with melena. There was no hemodynamic instability. Six patients had prior sclerotherapy. Esophageal varices, grades 1 (five patients) and 2 (three patients), were present. Severe PHG was encountered in seven patients. There was no correlation between the presence or absence of varices, the grade of esophageal varices, and prior sclerotherapv on the severity of PHG or continued bleeding. The mean hospital stay was 6 days. An average of 4 units of blood was transfused per patient (range, 2–8). Continued bleeding occurred in nine patients (75%), one of whom had mild PHG. Two patients with continued bleeding subsequently were diagnosed with portal hypertensive vasculopathy distal to the stomach. There was one episode of encephalopathy and no related mortality. Acute (overt) bleeding from PHG is uncommon, likely to recur, and can evolve into a pattern of chronic blood loss.

Original languageEnglish (US)
Pages (from-to)2030-2033
Number of pages4
JournalThe American Journal of Gastroenterology
Issue number12
StatePublished - Dec 1993

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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