Acute fatty liver of pregnancy associated with short-chain acyl-coenzyme A dehydrogenase deficiency

Dietrich Matern, Patricia Hart, Amy P. Murtha, Jerry Vockley, Niels Gregersen, David S. Millington, William R. Treem

Research output: Contribution to journalArticle

73 Scopus citations

Abstract

There is a correlation between pregnancy complications such as acute fatty liver of pregnancy and long-chain 3-hydroxyacyl-coenzyme A dehydrogenase (LCHAD) deficiency. We diagnosed another fatty acid β-oxidation defect, short-chain acyl-coenzyme A dehydrogenase deficiency, in an infant when evaluating him because his mother had acute fatty liver of pregnancy. Other β-oxidation defects, in addition to LCHAD deficiency, should be considered in children born after pregnancies complicated by liver disease.

Original languageEnglish (US)
Pages (from-to)585-588
Number of pages4
JournalJournal of Pediatrics
Volume138
Issue number4
DOIs
StatePublished - Jan 1 2001

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Matern, D., Hart, P., Murtha, A. P., Vockley, J., Gregersen, N., Millington, D. S., & Treem, W. R. (2001). Acute fatty liver of pregnancy associated with short-chain acyl-coenzyme A dehydrogenase deficiency. Journal of Pediatrics, 138(4), 585-588. https://doi.org/10.1067/mpd.2001.111814