Acute epidural spinal hemorrhage from vasculitis: Resolution with immunosuppression

Jeffrey T. Jacob; Shota Tanaka; Christopher P. Wood; Eelco F. Wijdicks; Giuseppe Lanzino

doi:10.1007/s12028-011-9667-8

Acute epidural spinal hemorrhage from vasculitis: Resolution with immunosuppression

Jeffrey T. Jacob, Shota Tanaka, Christopher P. Wood, Eelco F. Wijdicks, Giuseppe Lanzino

Radiology

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Background Angiographic vasculitis affecting the spine has been rarely described. The use of immunosuppression as a primary treatment and a review of the literature is presented. Methods Case report. Results A 61-year-old female presented with sudden onset back pain and headache. The patient was found to have acute spinal epidural hemorrhage and subsequent work-up demonstrated angiographic spinal vasculitis. Immunosuppression with cyclophosphamide resulted in clinical and radiographic improvement. Conclusions Immunomodulating therapy should be considered in the management of select patients with spinal vasculitis which may lead to improved clinical outcome and potentially disease resolution.

Original language	English (US)
Pages (from-to)	311-315
Number of pages	5
Journal	Neurocritical care
Volume	16
Issue number	2
DOIs	https://doi.org/10.1007/s12028-011-9667-8
State	Published - Apr 1 2012

Keywords

Spinal aneurysm
Spinal vasculitis
Subarachnoid hemorrhage

ASJC Scopus subject areas

Clinical Neurology
Critical Care and Intensive Care Medicine

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title = "Acute epidural spinal hemorrhage from vasculitis: Resolution with immunosuppression",

abstract = "Background Angiographic vasculitis affecting the spine has been rarely described. The use of immunosuppression as a primary treatment and a review of the literature is presented. Methods Case report. Results A 61-year-old female presented with sudden onset back pain and headache. The patient was found to have acute spinal epidural hemorrhage and subsequent work-up demonstrated angiographic spinal vasculitis. Immunosuppression with cyclophosphamide resulted in clinical and radiographic improvement. Conclusions Immunomodulating therapy should be considered in the management of select patients with spinal vasculitis which may lead to improved clinical outcome and potentially disease resolution.",

keywords = "Spinal aneurysm, Spinal vasculitis, Subarachnoid hemorrhage",

author = "Jacob, {Jeffrey T.} and Shota Tanaka and Wood, {Christopher P.} and Wijdicks, {Eelco F.} and Giuseppe Lanzino",

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doi = "10.1007/s12028-011-9667-8",

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T1 - Acute epidural spinal hemorrhage from vasculitis

T2 - Resolution with immunosuppression

AU - Jacob, Jeffrey T.

AU - Tanaka, Shota

AU - Wood, Christopher P.

AU - Wijdicks, Eelco F.

AU - Lanzino, Giuseppe

PY - 2012/4/1

Y1 - 2012/4/1

N2 - Background Angiographic vasculitis affecting the spine has been rarely described. The use of immunosuppression as a primary treatment and a review of the literature is presented. Methods Case report. Results A 61-year-old female presented with sudden onset back pain and headache. The patient was found to have acute spinal epidural hemorrhage and subsequent work-up demonstrated angiographic spinal vasculitis. Immunosuppression with cyclophosphamide resulted in clinical and radiographic improvement. Conclusions Immunomodulating therapy should be considered in the management of select patients with spinal vasculitis which may lead to improved clinical outcome and potentially disease resolution.

AB - Background Angiographic vasculitis affecting the spine has been rarely described. The use of immunosuppression as a primary treatment and a review of the literature is presented. Methods Case report. Results A 61-year-old female presented with sudden onset back pain and headache. The patient was found to have acute spinal epidural hemorrhage and subsequent work-up demonstrated angiographic spinal vasculitis. Immunosuppression with cyclophosphamide resulted in clinical and radiographic improvement. Conclusions Immunomodulating therapy should be considered in the management of select patients with spinal vasculitis which may lead to improved clinical outcome and potentially disease resolution.

KW - Spinal aneurysm

KW - Spinal vasculitis

KW - Subarachnoid hemorrhage

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Acute epidural spinal hemorrhage from vasculitis: Resolution with immunosuppression

Abstract

Keywords

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