TY - JOUR
T1 - Acute aortic dissection presenting with primarily abdominal pain
T2 - A rare manifestation of a deadly disease
AU - Upchurch, Gilbert R.
AU - Nienaber, Christoph
AU - Fattori, Rossella
AU - Evangelista, Arturo
AU - Oh, Jae
AU - Cooper, Jeanna V.
AU - Isselbacher, Eric
AU - Suzuki, Toru
AU - Eagle, Kim A.
N1 - Funding Information:
We thank Jeanna V. Cooper, MS, Jianming Fang, MD, and Dean E. Smith, PhD, University of Michigan Ann Arbor, MI, for data management and biostatistical support. The International Registry of Acute Aortic Dissection (IRAD) is supported by grants from the University of Michigan Health System and the Varbedian Fund for Aortic Research.
PY - 2005/5
Y1 - 2005/5
N2 - The objective of this study was to determine the morbidity and mortality of patients with acute thoracic aortic dissections who present primarily with abdominal pain. Nine hundred ninety-two patients (mean age, 62.1 years∈±∈14.1; 68% male) encountered from 1996 to 2001 with acute thoracic aortic dissections from the International Registry of acute Aortic Dissection were studied. Patient demographics, presenting symptoms, signs of aortic dissection, aortic pathology, and mortality were compared in patients presenting primarily with abdominal pain (group I, 46 patients, 4.6%) versus all others (group II). Demographics were similar between the two groups. When signs of aortic dissection were examined, 63% of patients in group I presented with hypertension compared to only 47% of patients in group II (p∈=∈0.04). Patients in group I were less likely to present with evidence of end-organ malperfusion. Importantly, mortality in patients with a type B dissection, specifically following surgery for the dissection, was significantly increased in patients who presented primarily with abdominal pain (group I, 28% mortality vs. group II, 10.2% mortality; p∈=∈0.02). This study documented increased mortality in patients with acute thoracic aortic dissections who present primarily with abdominal pain, underscoring the importance of maintaining a high index of suspicion for an aortic dissection in patients who have appropriate risk factors.
AB - The objective of this study was to determine the morbidity and mortality of patients with acute thoracic aortic dissections who present primarily with abdominal pain. Nine hundred ninety-two patients (mean age, 62.1 years∈±∈14.1; 68% male) encountered from 1996 to 2001 with acute thoracic aortic dissections from the International Registry of acute Aortic Dissection were studied. Patient demographics, presenting symptoms, signs of aortic dissection, aortic pathology, and mortality were compared in patients presenting primarily with abdominal pain (group I, 46 patients, 4.6%) versus all others (group II). Demographics were similar between the two groups. When signs of aortic dissection were examined, 63% of patients in group I presented with hypertension compared to only 47% of patients in group II (p∈=∈0.04). Patients in group I were less likely to present with evidence of end-organ malperfusion. Importantly, mortality in patients with a type B dissection, specifically following surgery for the dissection, was significantly increased in patients who presented primarily with abdominal pain (group I, 28% mortality vs. group II, 10.2% mortality; p∈=∈0.02). This study documented increased mortality in patients with acute thoracic aortic dissections who present primarily with abdominal pain, underscoring the importance of maintaining a high index of suspicion for an aortic dissection in patients who have appropriate risk factors.
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U2 - 10.1007/s10016-004-0171-x
DO - 10.1007/s10016-004-0171-x
M3 - Article
C2 - 15735946
AN - SCOPUS:21244439881
VL - 19
SP - 367
EP - 373
JO - Annals of Vascular Surgery
JF - Annals of Vascular Surgery
SN - 0890-5096
IS - 3
ER -