Original language | English (US) |
---|---|
Pages (from-to) | 849-850 |
Number of pages | 2 |
Journal | The Lancet |
Volume | 302 |
Issue number | 7833 |
DOIs | |
State | Published - Oct 13 1973 |
ASJC Scopus subject areas
- General Medicine
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In: The Lancet, Vol. 302, No. 7833, 13.10.1973, p. 849-850.
Research output: Contribution to journal › Letter › peer-review
}
TY - JOUR
T1 - ACUPUNCTURE ANÆSTHESIA
AU - Brennan, Robert W.
AU - Veldhuis, Johannes
AU - Chu, Richard
N1 - Funding Information: of patients at the National Cancer Institute (undoubtedly including many of the patients reported by Hirshaut et at.). Only 12 Burkitt’s lymphoma patients were reported by us then, in contrast to the 29 reported in our subsequent papers, but it is reassuring to find that Hirshaut et al.’s series confirms our finding that a number of American Burkitt’s lymphoma patients are negative. As of July 1, 1973, we have studied sera from 73 patients with Burkitt’s lymphoma and have found that the sera from 12 of these do not contain detectable antibodies to E.B. virus. The point that we have made in our previous publications that should be emphasised again, however, is that we are impressed by the number of American Burkitt’s lymphoma patients with high E.B.-virus titres not because we necessarily believe that E.B. virus causes Burkitt’s lymphoma but because this represents another parameter, in addition to the clinical features and time-space clus- tering 9,10 in which American and African Burkitt’s lymphomas are similar. Determination of the xtiology of Burkitt’s lymphoma is less likely to come through serology than through the detection of the viral genome in the patients’ tumours and not in controls. Some of these studies do continue to implicate E.B. virus as a possible cause of Burkitt’s lymphoma,"-13 although Klein’A has found two typical Burkitt tumour specimens from African patients that do not contain the E.B.-virus-associated nuclear antigen found in almost all other fresh tumours. We would agree with Hirshaut and his colleagues that it is still premature to assume that E.B. virus causes Burkitt’s tumour in any country, but we also think that it is premature to state that Burkitt’s tumour has a different astiotogy in Africa than it has in the United States. Public Health Service, National Institutes of Health, Bethesda, Maryland 20014, U.S.A.
PY - 1973/10/13
Y1 - 1973/10/13
UR - http://www.scopus.com/inward/record.url?scp=0015922521&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0015922521&partnerID=8YFLogxK
U2 - 10.1016/S0140-6736(73)90895-7
DO - 10.1016/S0140-6736(73)90895-7
M3 - Letter
C2 - 4126647
AN - SCOPUS:0015922521
SN - 0140-6736
VL - 302
SP - 849
EP - 850
JO - The Lancet
JF - The Lancet
IS - 7833
ER -