Activation of Rac1 by Src-dependent phosphorylation of Dock180 Y1811 mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans

Haizhong Feng, Bo Hu, Kun Wei Liu, Yanxin Li, Xinghua Lu, Tao Cheng, Jia Jean Yiin, Songjian Lu, Susan Keezer, Tim Fenton, Frank B. Furnari, Ronald L. Hamilton, Kristiina Vuori, Jann N. Sarkaria, Motoo Nagane, Ryo Nishikawa, Webster K. Cavenee, Shi Yuan Cheng

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Medicine & Life Sciences