Acromegaly: An endocrine society clinical practice guideline

Laurence Katznelson, Edward R. Laws, Shlomo Melmed, Mark E. Molitch, Mohammad Hassan Murad, Andrea Utz, John A.H. Wass

Research output: Contribution to journalReview article

630 Scopus citations

Abstract

Participants: The Task Force included a chair selected by the Endocrine Society Clinical Guidelines Subcommittee (CGS), five experts in the field, and a methodologist. The authors received no corporate funding or remuneration. This guideline is cosponsored by the European Society of Endocrinology.

Evidence: This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe both the strength of recommendations and the quality of evidence. The Task Force reviewed primary evidence and commissioned two additional systematic reviews.

Consensus Process: One group meeting, several conference calls, and e-mail communications enabled consensus. Committees and members of the Endocrine Society and the European Society of Endocrinology reviewed drafts of the guidelines.

Conclusions: Using an evidence-based approach, this acromegaly guideline addresses important clinical issues regarding the evaluation and management of acromegaly, including the appropriate biochemical assessment, a therapeutic algorithm, including use of medical monotherapy or combination therapy, and management during pregnancy.

Objective: The aim was to formulate clinical practice guidelines for acromegaly.

Original languageEnglish (US)
Pages (from-to)3933-3951
Number of pages19
JournalJournal of Clinical Endocrinology and Metabolism
Volume99
Issue number11
DOIs
StatePublished - Nov 1 2014

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

Fingerprint Dive into the research topics of 'Acromegaly: An endocrine society clinical practice guideline'. Together they form a unique fingerprint.

  • Cite this

    Katznelson, L., Laws, E. R., Melmed, S., Molitch, M. E., Murad, M. H., Utz, A., & Wass, J. A. H. (2014). Acromegaly: An endocrine society clinical practice guideline. Journal of Clinical Endocrinology and Metabolism, 99(11), 3933-3951. https://doi.org/10.1210/jc.2014-2700