Acrocyanosis from phenazopyridine-induced sulfhemoglobinemia mistaken for raynaud phenomenon

Tanaz A. Kermani, Sorin V. Pislaru, Thomas G. Osborn

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Rheumatologists are often asked to evaluate patients with Raynaud phenomenon. Occasionally, an alternate explanation is revealed such as acrocyanosis. Methemoglobinemia and sulfhemoglobinemia are rare causes of cyanosis that can be medication-induced. Both are known complications of therapy with phenazopyridine. We report an unusual case of a 45-year-old woman in whom sulfhemoglobinemia from chronic therapy with phenazopyridine was misdiagnosed as due to Raynaud phenomenon and limited scleroderma. This case illustrates the importance of taking into account medication-related adverse events when evaluating patients with Raynaud-like phenomenon.

Original languageEnglish (US)
Pages (from-to)127-129
Number of pages3
JournalJournal of Clinical Rheumatology
Volume15
Issue number3
DOIs
StatePublished - Apr 1 2009

Keywords

  • Acrocyanosis
  • Phenazopyridine
  • Sulfhemoglobinemia

ASJC Scopus subject areas

  • Rheumatology

Fingerprint Dive into the research topics of 'Acrocyanosis from phenazopyridine-induced sulfhemoglobinemia mistaken for raynaud phenomenon'. Together they form a unique fingerprint.

  • Cite this