Accurate determination of breast cancer size

The role of histopathology and imaging

Bobbi Pritt, Donald L. Weaver

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

One critical role played by the pathologist in contemporary breast cancer management is that of providing accurate tumour measurements for staging and prognosis. Numerous factors have the potential to affect the final pathologist-recorded tumour size including diligence in measurement, tumour histology and growth pattern, tissue fixation and processing, prior biopsy and prior therapy. The pathologist should strive to provide three-dimensional tumour measurements in 0.1 cm increments from the gross specimen and then confirm these measurements microscopically whenever possible. In the era of breast conservation and emerging ablative therapies, the pathologist should also be familiar with the size-determining capability of various breast imaging techniques and their correlation with pathology. In determining final dimension, the pathologist is in a favourable position to verify or modify the size of a breast tumour based on the sum of information from all pathology specimens and, if appropriate, to correlate size with the patient's imaging studies.

Original languageEnglish (US)
Pages (from-to)435-442
Number of pages8
JournalCurrent Diagnostic Pathology
Volume11
Issue number6
DOIs
StatePublished - Dec 2005
Externally publishedYes

Fingerprint

Breast Neoplasms
Breast
Tissue Fixation
Pathology
Neoplasms
Neoplasm Staging
Histology
Pathologists
Biopsy
Therapeutics
Growth

Keywords

  • Breast cancer
  • Imaging
  • Measurement
  • Size
  • Staging
  • Ultrasonography

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Accurate determination of breast cancer size : The role of histopathology and imaging. / Pritt, Bobbi; Weaver, Donald L.

In: Current Diagnostic Pathology, Vol. 11, No. 6, 12.2005, p. 435-442.

Research output: Contribution to journalReview article

Pritt, Bobbi ; Weaver, Donald L. / Accurate determination of breast cancer size : The role of histopathology and imaging. In: Current Diagnostic Pathology. 2005 ; Vol. 11, No. 6. pp. 435-442.
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