Absorbable intramedullary implants for hand fractures. Animal experiments and clinical trial

S. M. Kumta, R. Spinner, P. C. Leung

Research output: Contribution to journalArticle

45 Scopus citations

Abstract

Biodegradable implants made from polyglycolic and polylactic acid co-polymers undergo degradation by hydrolysis which results in loss of their mechanical strength. The degradation of 1.5 mm polyglycolide rods (Biofix) was studied after intramedullary and subcutaneous implantation in rabbits. Two weeks after implantation there was a 73% reduction in strength of the intramedullary implants and a 64% reduction in the subcutaneous implants. Polyglycolide implants were compared with Kirschner wires for intramedullary fixation of extraarticular fractures in the hand. In one group of patients fractures were fixed with a 1.5 mm intramedullary rod and in a similar group a Kirschner wire was used. In both a wire loop was added for extra fixation. At six months there was no significant difference between the two groups. There were no allergic reactions to the polyglycolide implants.

Original languageEnglish (US)
Pages (from-to)563-566
Number of pages4
JournalJournal of Bone and Joint Surgery - Series B
Volume74
Issue number4
StatePublished - 1992
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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