Absent prolactin response to L-tryptophan in normal and acromegalic subjects

A. R. Glass, Robert Christian Smallridge, M. Schaaf, R. C. Dimond

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

L-tryptophan (5 g orally), the precursor of serotonin, was administered to 10 patients with acromegaly and 8 control subjects. In normal subjects, there was no significant change in serum prolactin after L-tryptophan. In subjects with acromegaly, there was no significant net change in serum prolactin after L-tryptophan relative either to the baseline value before L-tryptophan or to values obtained on a control day without L-tryptophan. Activation of serotoninergic pathways by oral administration of the serotonin precursor L-tryptophan has no effect on serum prolactin in normal or acromegalic subjects.

Original languageEnglish (US)
Pages (from-to)261-265
Number of pages5
JournalPsychoneuroendocrinology
Volume5
Issue number3
DOIs
StatePublished - 1980
Externally publishedYes

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Tryptophan
Prolactin
Acromegaly
Serotonin
Serum
Oral Administration

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Psychiatry and Mental health
  • Biological Psychiatry
  • Endocrine and Autonomic Systems
  • Psychology(all)

Cite this

Absent prolactin response to L-tryptophan in normal and acromegalic subjects. / Glass, A. R.; Smallridge, Robert Christian; Schaaf, M.; Dimond, R. C.

In: Psychoneuroendocrinology, Vol. 5, No. 3, 1980, p. 261-265.

Research output: Contribution to journalArticle

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