Absent pachymeningeal gadolinium enhancement on cranial MRI despite symptomatic CSF leak

Bahram Mokri, J. L.D. Atkinson, D. W. Dodick, G. M. Miller, D. G. Piepgras

Research output: Contribution to journalArticle

64 Scopus citations

Abstract

CSF leak is recognized to cause orthostatic headaches and diffuse pachymeningeal gadolinium enhancement (DPMGE) on MRI. We report six patients with typical symptoms and documented CSF leaks without DPMGE. Two had normal meninges from the onset; one initially had normal meninges, but subsequently DPMGE developed. In three, the initially noted DPMGE resolved while they were still symptomatic with documented continued CSF leaks. Absent DPMGE does not rule out CSF leak. When clinical manifestations suggest this disorder, additional diagnostic studies should be pursued.

Original languageEnglish (US)
Pages (from-to)402-404
Number of pages3
JournalNeurology
Volume53
Issue number2
StatePublished - Jul 22 1999

ASJC Scopus subject areas

  • Clinical Neurology

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  • Cite this

    Mokri, B., Atkinson, J. L. D., Dodick, D. W., Miller, G. M., & Piepgras, D. G. (1999). Absent pachymeningeal gadolinium enhancement on cranial MRI despite symptomatic CSF leak. Neurology, 53(2), 402-404.