Abnormal visual contrast acuity in Parkinson's disease

Tanya P. Lin, Heather Rigby, Jennifer S. Adler, Joseph G. Hentz, Laura J. Balcer, Steven L. Galetta, Steve Devick, Richard Cronin, Charles Howard Adler

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Background: Low-contrast vision is thought to be reduced in Parkinson's disease (PD). This may have a direct impact on quality of life such as driving, using tools, finding objects, and mobility in low-light condition. Low-contrast letter acuity testing has been successful in assessing low-contrast vision in multiple sclerosis. We report the use of a new iPad application to measure low-contrast acuity in patients with PD. Objective: To evaluate low- and high-contrast letter acuity in PD patients and controls using a variable contrast acuity eye chart developed for the Apple iPad. Methods: Thirty-two PD and 71 control subjects were studied. Subjects viewed the Variable Contrast Acuity Chart on an iPad with both eyes open at two distances (40 cm and 2 m) and at high contrast (black and white visual acuity) and 2.5% low contrast. Acuity scores for the two groups were compared. Results: PD patients had significantly lower scores (indicating worse vision) for 2.5% low contrast at both distances and for high contrast at 2 m (p < 0.003) compared to controls. No significant difference was found between the two groups for high contrast at 40 cm (p = 0.12). Conclusions: Parkinson's disease patients have reduced low and high contrast acuity compared to controls. An iPad app, as used in this study, could serve as a quick screening tool to complement more formal testing of patients with PD and other neurologic disorders.

Original languageEnglish (US)
Pages (from-to)125-130
Number of pages6
JournalJournal of Parkinson's Disease
Volume5
Issue number1
DOIs
StatePublished - 2015

Fingerprint

Visual Acuity
Parkinson Disease
Low Vision
Patient Acuity
Malus
Nervous System Diseases
Multiple Sclerosis
Quality of Life
Light

Keywords

  • contrast sensitivity
  • Parkinson's disease
  • vision
  • visual acuity

ASJC Scopus subject areas

  • Clinical Neurology
  • Cellular and Molecular Neuroscience

Cite this

Lin, T. P., Rigby, H., Adler, J. S., Hentz, J. G., Balcer, L. J., Galetta, S. L., ... Adler, C. H. (2015). Abnormal visual contrast acuity in Parkinson's disease. Journal of Parkinson's Disease, 5(1), 125-130. https://doi.org/10.3233/JPD-140470

Abnormal visual contrast acuity in Parkinson's disease. / Lin, Tanya P.; Rigby, Heather; Adler, Jennifer S.; Hentz, Joseph G.; Balcer, Laura J.; Galetta, Steven L.; Devick, Steve; Cronin, Richard; Adler, Charles Howard.

In: Journal of Parkinson's Disease, Vol. 5, No. 1, 2015, p. 125-130.

Research output: Contribution to journalArticle

Lin, TP, Rigby, H, Adler, JS, Hentz, JG, Balcer, LJ, Galetta, SL, Devick, S, Cronin, R & Adler, CH 2015, 'Abnormal visual contrast acuity in Parkinson's disease', Journal of Parkinson's Disease, vol. 5, no. 1, pp. 125-130. https://doi.org/10.3233/JPD-140470
Lin TP, Rigby H, Adler JS, Hentz JG, Balcer LJ, Galetta SL et al. Abnormal visual contrast acuity in Parkinson's disease. Journal of Parkinson's Disease. 2015;5(1):125-130. https://doi.org/10.3233/JPD-140470
Lin, Tanya P. ; Rigby, Heather ; Adler, Jennifer S. ; Hentz, Joseph G. ; Balcer, Laura J. ; Galetta, Steven L. ; Devick, Steve ; Cronin, Richard ; Adler, Charles Howard. / Abnormal visual contrast acuity in Parkinson's disease. In: Journal of Parkinson's Disease. 2015 ; Vol. 5, No. 1. pp. 125-130.
@article{0dcfce58e82c4eb6a85ad79b9da8c8b3,
title = "Abnormal visual contrast acuity in Parkinson's disease",
abstract = "Background: Low-contrast vision is thought to be reduced in Parkinson's disease (PD). This may have a direct impact on quality of life such as driving, using tools, finding objects, and mobility in low-light condition. Low-contrast letter acuity testing has been successful in assessing low-contrast vision in multiple sclerosis. We report the use of a new iPad application to measure low-contrast acuity in patients with PD. Objective: To evaluate low- and high-contrast letter acuity in PD patients and controls using a variable contrast acuity eye chart developed for the Apple iPad. Methods: Thirty-two PD and 71 control subjects were studied. Subjects viewed the Variable Contrast Acuity Chart on an iPad with both eyes open at two distances (40 cm and 2 m) and at high contrast (black and white visual acuity) and 2.5{\%} low contrast. Acuity scores for the two groups were compared. Results: PD patients had significantly lower scores (indicating worse vision) for 2.5{\%} low contrast at both distances and for high contrast at 2 m (p < 0.003) compared to controls. No significant difference was found between the two groups for high contrast at 40 cm (p = 0.12). Conclusions: Parkinson's disease patients have reduced low and high contrast acuity compared to controls. An iPad app, as used in this study, could serve as a quick screening tool to complement more formal testing of patients with PD and other neurologic disorders.",
keywords = "contrast sensitivity, Parkinson's disease, vision, visual acuity",
author = "Lin, {Tanya P.} and Heather Rigby and Adler, {Jennifer S.} and Hentz, {Joseph G.} and Balcer, {Laura J.} and Galetta, {Steven L.} and Steve Devick and Richard Cronin and Adler, {Charles Howard}",
year = "2015",
doi = "10.3233/JPD-140470",
language = "English (US)",
volume = "5",
pages = "125--130",
journal = "Journal of Parkinson's Disease",
issn = "1877-7171",
publisher = "IOS Press",
number = "1",

}

TY - JOUR

T1 - Abnormal visual contrast acuity in Parkinson's disease

AU - Lin, Tanya P.

AU - Rigby, Heather

AU - Adler, Jennifer S.

AU - Hentz, Joseph G.

AU - Balcer, Laura J.

AU - Galetta, Steven L.

AU - Devick, Steve

AU - Cronin, Richard

AU - Adler, Charles Howard

PY - 2015

Y1 - 2015

N2 - Background: Low-contrast vision is thought to be reduced in Parkinson's disease (PD). This may have a direct impact on quality of life such as driving, using tools, finding objects, and mobility in low-light condition. Low-contrast letter acuity testing has been successful in assessing low-contrast vision in multiple sclerosis. We report the use of a new iPad application to measure low-contrast acuity in patients with PD. Objective: To evaluate low- and high-contrast letter acuity in PD patients and controls using a variable contrast acuity eye chart developed for the Apple iPad. Methods: Thirty-two PD and 71 control subjects were studied. Subjects viewed the Variable Contrast Acuity Chart on an iPad with both eyes open at two distances (40 cm and 2 m) and at high contrast (black and white visual acuity) and 2.5% low contrast. Acuity scores for the two groups were compared. Results: PD patients had significantly lower scores (indicating worse vision) for 2.5% low contrast at both distances and for high contrast at 2 m (p < 0.003) compared to controls. No significant difference was found between the two groups for high contrast at 40 cm (p = 0.12). Conclusions: Parkinson's disease patients have reduced low and high contrast acuity compared to controls. An iPad app, as used in this study, could serve as a quick screening tool to complement more formal testing of patients with PD and other neurologic disorders.

AB - Background: Low-contrast vision is thought to be reduced in Parkinson's disease (PD). This may have a direct impact on quality of life such as driving, using tools, finding objects, and mobility in low-light condition. Low-contrast letter acuity testing has been successful in assessing low-contrast vision in multiple sclerosis. We report the use of a new iPad application to measure low-contrast acuity in patients with PD. Objective: To evaluate low- and high-contrast letter acuity in PD patients and controls using a variable contrast acuity eye chart developed for the Apple iPad. Methods: Thirty-two PD and 71 control subjects were studied. Subjects viewed the Variable Contrast Acuity Chart on an iPad with both eyes open at two distances (40 cm and 2 m) and at high contrast (black and white visual acuity) and 2.5% low contrast. Acuity scores for the two groups were compared. Results: PD patients had significantly lower scores (indicating worse vision) for 2.5% low contrast at both distances and for high contrast at 2 m (p < 0.003) compared to controls. No significant difference was found between the two groups for high contrast at 40 cm (p = 0.12). Conclusions: Parkinson's disease patients have reduced low and high contrast acuity compared to controls. An iPad app, as used in this study, could serve as a quick screening tool to complement more formal testing of patients with PD and other neurologic disorders.

KW - contrast sensitivity

KW - Parkinson's disease

KW - vision

KW - visual acuity

UR - http://www.scopus.com/inward/record.url?scp=84923177783&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84923177783&partnerID=8YFLogxK

U2 - 10.3233/JPD-140470

DO - 10.3233/JPD-140470

M3 - Article

C2 - 25425583

AN - SCOPUS:84923177783

VL - 5

SP - 125

EP - 130

JO - Journal of Parkinson's Disease

JF - Journal of Parkinson's Disease

SN - 1877-7171

IS - 1

ER -