A transient increase in junctional acetylcholine receptors after denervation

A. Olek, S. Younkin, R. M. Slugg, M. Konieczkowski, N. Robbins

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

An improved method for assaying acetylcholine (ACh) receptors at the neuromuscular junction has been used to examine the effects of denervation in the rat diaphragm. An early increase of junctional ACh receptors occurred after two days of denervation followed by a decline at 14 days. Possible mechanisms responsible for this transient increase in junctional ACh receptors are discussed.

Original languageEnglish (US)
Pages (from-to)429-432
Number of pages4
JournalBrain Research
Volume214
Issue number2
DOIs
StatePublished - Jun 15 1981

Keywords

  • ACh receptor
  • denervation
  • neuromuscular junction
  • rat diaphragm
  • transient increase

ASJC Scopus subject areas

  • General Neuroscience
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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