A secondary progressive clinical course is uncommon in neuromyelitis optica

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206 Scopus citations

Abstract

We compared the clinical course of 96 patients with neuromyelitis optica (NMO) to multiple sclerosis (MS) natural history data. Based on the distribution of follow-up data (median 6.1 year), we estimated that 21 NMO patients would convert to a secondary progressive course, but we observed only two conversions (p = 0.00002; relative risk = 0.08). The disparate natural histories of MS and NMO suggest dissociation between relapses and clinical progression in CNS demyelinating diseases.

Original languageEnglish (US)
Pages (from-to)603-605
Number of pages3
JournalNeurology
Volume68
Issue number8
DOIs
StatePublished - Feb 1 2007

ASJC Scopus subject areas

  • Clinical Neurology

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