TY - JOUR
T1 - A review of the growing evidence base for pediatric psychopharmacology
AU - Pappadopulos, Elizabeth A.
AU - Tate Guelzow, B.
AU - Wong, Carrie
AU - Ortega, Melissa
AU - Jensen, Peter S.
PY - 2004/10
Y1 - 2004/10
N2 - This article provides an update of pediatric psychopharmacologic treatment evidence and focuses on six classes of medications in pediatric populations: psychostimulants, mood stabilizers, SSRIs, tricyclic antidepressants, antipsychotic agents, and other agents. The evidence is organized by disorder so that it is most useful to practicing clinicians. We begin each section with a brief introduction and summary of the findings published before January 1998. Priority is given to clinical trials that use random assignment and use of a comparison group (ie, placebo-control, head-to-head comparison, or cross-over design). Serious concerns remain about the efficacy and safety of many of these agents for use in children and adolescents. While a great progress is being made, there is clearly much work left to be done.
AB - This article provides an update of pediatric psychopharmacologic treatment evidence and focuses on six classes of medications in pediatric populations: psychostimulants, mood stabilizers, SSRIs, tricyclic antidepressants, antipsychotic agents, and other agents. The evidence is organized by disorder so that it is most useful to practicing clinicians. We begin each section with a brief introduction and summary of the findings published before January 1998. Priority is given to clinical trials that use random assignment and use of a comparison group (ie, placebo-control, head-to-head comparison, or cross-over design). Serious concerns remain about the efficacy and safety of many of these agents for use in children and adolescents. While a great progress is being made, there is clearly much work left to be done.
UR - http://www.scopus.com/inward/record.url?scp=4544336635&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=4544336635&partnerID=8YFLogxK
U2 - 10.1016/j.chc.2004.04.007
DO - 10.1016/j.chc.2004.04.007
M3 - Review article
C2 - 15380785
AN - SCOPUS:4544336635
SN - 1056-4993
VL - 13
SP - 817
EP - 855
JO - Child and Adolescent Psychiatric Clinics of North America
JF - Child and Adolescent Psychiatric Clinics of North America
IS - 4
ER -