A resilience intervention involving mindfulness training for transplant patients and their caregivers

Cynthia M. Stonnington, Betty Darby, Angela Santucci, Pamela Mulligan, Patricia Pathuis, Andrea Cuc, Joseph G. Hentz, Nan Zhang, David Mulligan, Amit Sood

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Solid organ and stem cell transplant patients and their caregivers report a substantial level of distress. Mindfulness-based stress reduction has been shown to alleviate distress associated with transplant, but there is limited experience in this population with other mindfulness-based interventions, or with combined transplant patient and caregiver interventions. We evaluated a novel, 6-week mindfulness-based resilience training (MBRT) class for transplant patients and their caregivers that incorporates mindfulness practice, yoga, and neuroscience of stress and resilience. Thirty-one heart, liver, kidney/pancreas, and stem cell transplant patients and 18 caregivers at Mayo Clinic in Arizona participated. Measures of stress, resilience, depression, anxiety, health-related quality of life, positive and negative affect, and sleep were completed at baseline, 6 weeks, and 3 months postintervention. At 6 weeks and 3 months, patients demonstrated significant (P<.005) improvements from baseline in measures of perceived stress, depression, anxiety, and negative affect. Quality-of-life mental component (P=.006) and positive affect (P=.02) also improved at follow-up. Most participants adhered to the program, were satisfied with class length and frequency, and reported improved well-being as a result of the class. MBRT holds promise as an intervention to enhance resilience and manage stress for transplant patients and their caregivers.

Original languageEnglish (US)
Pages (from-to)1466-1472
Number of pages7
JournalClinical Transplantation
Volume30
Issue number11
DOIs
StatePublished - Nov 1 2016

Keywords

  • caregivers
  • mindfulness
  • resilience
  • stress
  • transplant recipients

ASJC Scopus subject areas

  • Transplantation

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