A resilience intervention involving mindfulness training for transplant patients and their caregivers

Cynthia M Stonnington, Betty Darby, Angela Santucci, Pamela Mulligan, Patricia Pathuis, Andrea Cuc, Joseph G. Hentz, Nan Zhang, David Mulligan, Amit Sood

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Solid organ and stem cell transplant patients and their caregivers report a substantial level of distress. Mindfulness-based stress reduction has been shown to alleviate distress associated with transplant, but there is limited experience in this population with other mindfulness-based interventions, or with combined transplant patient and caregiver interventions. We evaluated a novel, 6-week mindfulness-based resilience training (MBRT) class for transplant patients and their caregivers that incorporates mindfulness practice, yoga, and neuroscience of stress and resilience. Thirty-one heart, liver, kidney/pancreas, and stem cell transplant patients and 18 caregivers at Mayo Clinic in Arizona participated. Measures of stress, resilience, depression, anxiety, health-related quality of life, positive and negative affect, and sleep were completed at baseline, 6 weeks, and 3 months postintervention. At 6 weeks and 3 months, patients demonstrated significant (P<.005) improvements from baseline in measures of perceived stress, depression, anxiety, and negative affect. Quality-of-life mental component (P=.006) and positive affect (P=.02) also improved at follow-up. Most participants adhered to the program, were satisfied with class length and frequency, and reported improved well-being as a result of the class. MBRT holds promise as an intervention to enhance resilience and manage stress for transplant patients and their caregivers.

Original languageEnglish (US)
Pages (from-to)1466-1472
Number of pages7
JournalClinical Transplantation
Volume30
Issue number11
DOIs
StatePublished - Nov 1 2016

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Keywords

  • caregivers
  • mindfulness
  • resilience
  • stress
  • transplant recipients

ASJC Scopus subject areas

  • Transplantation

Cite this

Stonnington, C. M., Darby, B., Santucci, A., Mulligan, P., Pathuis, P., Cuc, A., Hentz, J. G., Zhang, N., Mulligan, D., & Sood, A. (2016). A resilience intervention involving mindfulness training for transplant patients and their caregivers. Clinical Transplantation, 30(11), 1466-1472. https://doi.org/10.1111/ctr.12841