A reliability study of SLEDAI: A disease activity index for systemic lupus erythematosus

G. Hawker, S. Gabriel, C. Bombardier, C. Goldsmith, D. Caron, D. Gladman

Research output: Contribution to journalArticle

138 Scopus citations

Abstract

SLEDAI, a disease activity index for systemic lupus erythematosus (SLE) has been validated against other such indices and its reliability has been shown by specialists in SLE. To assess its reliability among less experienced clinicians, we conducted a reliability study with 3 rheumatology trainees and 9 patients with SLE according to a Latin square design. SLEDAI easily distinguished between patients (p = 0.0009), and physician variability was not statistically significant (p = 0.27). Inter and intraobserver agreement were 78.7 and 98.0% , respectively. SLEDAI was thus shown to be a reliable instrument among less experienced observers for the assessment of disease activity in SLE.

Original languageEnglish (US)
Pages (from-to)657-660
Number of pages4
JournalJournal of Rheumatology
Volume20
Issue number4
StatePublished - Jan 1 1993

Keywords

  • SLEDAI
  • lupus disease activity
  • outcome measures

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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    Hawker, G., Gabriel, S., Bombardier, C., Goldsmith, C., Caron, D., & Gladman, D. (1993). A reliability study of SLEDAI: A disease activity index for systemic lupus erythematosus. Journal of Rheumatology, 20(4), 657-660.