A Rare Pediatric Example of Subcutaneous Extraskeletal Osteosarcoma: A Case Report and Review of the Morphologic Differential Diagnosis

Riyam T. Zreik, Reid G. Meyer, Robert Brian Jenkins, Germán A. Norambuena, Karen J. Fritchie

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

ABSTRACT:: Primary extraskeletal osteosarcoma is an exceedingly rare malignant neoplasm that accounts for approximately 1% of soft tissue sarcomas and most often occurs in the deep soft tissues of adults. Extraskeletal osteosarcoma is characterized by the production of osteoid, bone, and/or chondroid matrix. The diagnosis of extraskeletal osteosarcoma requires careful radiologic and clinical correlation to ensure that the patient does not have an underlying bone primary. This is a case report of primary subcutaneous extraskeletal osteosarcoma arising in the thigh of a 15-year-old girl with a complex karyotype, and the morphologic differential diagnosis is reviewed.

Original languageEnglish (US)
JournalAmerican Journal of Dermatopathology
DOIs
StateAccepted/In press - Oct 12 2015

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Osteosarcoma
Differential Diagnosis
Pediatrics
Bone and Bones
Thigh
Karyotype
Sarcoma
Neoplasms

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Dermatology

Cite this

A Rare Pediatric Example of Subcutaneous Extraskeletal Osteosarcoma : A Case Report and Review of the Morphologic Differential Diagnosis. / Zreik, Riyam T.; Meyer, Reid G.; Jenkins, Robert Brian; Norambuena, Germán A.; Fritchie, Karen J.

In: American Journal of Dermatopathology, 12.10.2015.

Research output: Contribution to journalArticle

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