A rare case of childhood mucous membrane pemphigoid involving the oral and genital mucosa

Katinna Rodriguez Baisi; Ashley Wentworth; Asma J. Chattha; David J. DiCaudo; Aaron Mangold; Steven A. Nelson; Elaine Siegfried; Carilyn N. Wieland; Megha Tollefson

doi:10.1111/pde.14627

A rare case of childhood mucous membrane pemphigoid involving the oral and genital mucosa

Katinna Rodriguez Baisi, Ashley Wentworth, Asma J. Chattha, David J. DiCaudo, Aaron Mangold, Steven A. Nelson, Elaine Siegfried, Carilyn N. Wieland, Megha Tollefson

Research output: Contribution to journal › Article › peer-review

Abstract

Mucous membrane pemphigoid (MMP) is a rare chronic immunobullous disease that involves the mucous membranes and may result in significant scarring and complications if diagnosis is delayed. MMP typically occurs in elderly patients, with very few cases reported in children. Here, we present a 12-year-old female patient with childhood-onset oral and genital MMP, clinically suspected to be lichen sclerosus, but eventually diagnosed as MMP after multiple supportive biopsies and confirmatory direct immunofluorescence. Although treatment was challenging, the combined use of systemic corticosteroids, dapsone, and mycophenolate mofetil was ultimately successful in achieving disease control.

Original language	English (US)
Pages (from-to)	904-907
Number of pages	4
Journal	Pediatric Dermatology
Volume	38
Issue number	4
DOIs	https://doi.org/10.1111/pde.14627
State	Published - Jul 1 2021

Keywords

immunobullous disease
mucous membrane disorders

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Dermatology

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10.1111/pde.14627

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abstract = "Mucous membrane pemphigoid (MMP) is a rare chronic immunobullous disease that involves the mucous membranes and may result in significant scarring and complications if diagnosis is delayed. MMP typically occurs in elderly patients, with very few cases reported in children. Here, we present a 12-year-old female patient with childhood-onset oral and genital MMP, clinically suspected to be lichen sclerosus, but eventually diagnosed as MMP after multiple supportive biopsies and confirmatory direct immunofluorescence. Although treatment was challenging, the combined use of systemic corticosteroids, dapsone, and mycophenolate mofetil was ultimately successful in achieving disease control.",

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AU - Rodriguez Baisi, Katinna

AU - Wentworth, Ashley

AU - Chattha, Asma J.

AU - DiCaudo, David J.

AU - Mangold, Aaron

AU - Nelson, Steven A.

AU - Siegfried, Elaine

AU - Wieland, Carilyn N.

AU - Tollefson, Megha

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AB - Mucous membrane pemphigoid (MMP) is a rare chronic immunobullous disease that involves the mucous membranes and may result in significant scarring and complications if diagnosis is delayed. MMP typically occurs in elderly patients, with very few cases reported in children. Here, we present a 12-year-old female patient with childhood-onset oral and genital MMP, clinically suspected to be lichen sclerosus, but eventually diagnosed as MMP after multiple supportive biopsies and confirmatory direct immunofluorescence. Although treatment was challenging, the combined use of systemic corticosteroids, dapsone, and mycophenolate mofetil was ultimately successful in achieving disease control.

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A rare case of childhood mucous membrane pemphigoid involving the oral and genital mucosa

Abstract

Keywords

ASJC Scopus subject areas

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