A randomized trial of patching regimens for treatment of moderate amblyopia in children

Michael X. Repka, Roy W. Beck, Jonathan M Holmes, Eileen E. Birch, Danielle L. Chandler, Susan A. Cotter, Richard W. Hertle, Raymond T. Kraker, Pamela S. Moke, Graham E. Quinn, Mitchell M. Scheiman

Research output: Contribution to journalArticle

249 Citations (Scopus)

Abstract

Objective: To compare 2 hours vs 6 hours of daily patching as treatments for moderate amblyopia in children younger than 7 years. Methods: In a randomized multicenter (35 sites) clinical trial, 189 children younger than 7 years with amblyopia in the range of 20/40 to 20/80 were assigned to receive either 2 hours or 6 hours of daily patching combined with at least 1 hour per day of near visual activities during patching. Main Outcome Measure: Visual acuity in the amblyopic eye after 4 months. Results: Visual acuity in the amblyopic eye improved a similar amount in both groups. The improvement in the visual acuity of the amblyopic eye from baseline to 4 months averaged 2.40 lines in each group (P=.98). The 4-month visual acuity was at least 20/32 and/or improved from baseline by 3 or more lines in 62% of patients in each group (P>.99). Conclusion: When combined with prescribing 1 hour of near visual activities, 2 hours of daily patching produces an improvement in visual acuity that is of similar magnitude to the improvement produced by 6 hours of daily patching in treating moderate amblyopia in children aged 3 to 7 years.

Original languageEnglish (US)
Pages (from-to)603-611
Number of pages9
JournalArchives of Ophthalmology
Volume121
Issue number5
DOIs
StatePublished - May 1 2003

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Amblyopia
Visual Acuity
Therapeutics
Outcome Assessment (Health Care)
Clinical Trials

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Repka, M. X., Beck, R. W., Holmes, J. M., Birch, E. E., Chandler, D. L., Cotter, S. A., ... Scheiman, M. M. (2003). A randomized trial of patching regimens for treatment of moderate amblyopia in children. Archives of Ophthalmology, 121(5), 603-611. https://doi.org/10.1001/archopht.121.5.603

A randomized trial of patching regimens for treatment of moderate amblyopia in children. / Repka, Michael X.; Beck, Roy W.; Holmes, Jonathan M; Birch, Eileen E.; Chandler, Danielle L.; Cotter, Susan A.; Hertle, Richard W.; Kraker, Raymond T.; Moke, Pamela S.; Quinn, Graham E.; Scheiman, Mitchell M.

In: Archives of Ophthalmology, Vol. 121, No. 5, 01.05.2003, p. 603-611.

Research output: Contribution to journalArticle

Repka, MX, Beck, RW, Holmes, JM, Birch, EE, Chandler, DL, Cotter, SA, Hertle, RW, Kraker, RT, Moke, PS, Quinn, GE & Scheiman, MM 2003, 'A randomized trial of patching regimens for treatment of moderate amblyopia in children', Archives of Ophthalmology, vol. 121, no. 5, pp. 603-611. https://doi.org/10.1001/archopht.121.5.603
Repka, Michael X. ; Beck, Roy W. ; Holmes, Jonathan M ; Birch, Eileen E. ; Chandler, Danielle L. ; Cotter, Susan A. ; Hertle, Richard W. ; Kraker, Raymond T. ; Moke, Pamela S. ; Quinn, Graham E. ; Scheiman, Mitchell M. / A randomized trial of patching regimens for treatment of moderate amblyopia in children. In: Archives of Ophthalmology. 2003 ; Vol. 121, No. 5. pp. 603-611.
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