A proton magnetic relaxation study of the interaction of isolated sheep methaemoglobins A, B and C with inositol hexaphosphate

S. Vuk-Pavlović, B. Benko, G. D. Efremov, B. Markovska

Research output: Contribution to journalArticle

Abstract

1. 1. Sheep aquomethaemoglobins A and B exert similar paramagnetic influence on the solventproton magnetic relaxation (PMR) rates as observed in human HbA, even in the presence of inositol hexaphosphate (IHP). 2. 2. On the other hand, phosphate-free methaemoglobin C induces smaller PMR rates due to the restricted haem-accessibility. 3. 3. Here IHP also binds, although with smaller affinity and with different structural consequences from the other two sheep haemoglobins. Some implications of these findings are discussed here.

Original languageEnglish (US)
Pages (from-to)235-237
Number of pages3
JournalInternational Journal of Biochemistry
Volume7
Issue number5
DOIs
StatePublished - 1976
Externally publishedYes

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Magnetic relaxation
Phytic Acid
Protons
Sheep
Methemoglobin
Heme
Hemoglobins
Phosphates
methemoglobin A
aquomethemoglobin

ASJC Scopus subject areas

  • Biochemistry

Cite this

A proton magnetic relaxation study of the interaction of isolated sheep methaemoglobins A, B and C with inositol hexaphosphate. / Vuk-Pavlović, S.; Benko, B.; Efremov, G. D.; Markovska, B.

In: International Journal of Biochemistry, Vol. 7, No. 5, 1976, p. 235-237.

Research output: Contribution to journalArticle

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AU - Efremov, G. D.

AU - Markovska, B.

PY - 1976

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