A prospective survey for central line skin-site colonization by the pathogen Malassezia furfur among hospitalized adults receiving total parenteral nutrition

Aminah Jatoi, Karen Hanjosten, Elizabeth Ross, Joel B. Mason

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Over 50 case reports suggest that Malassezia furfur is an emerging systemic pathogen in neonates who receive IV lipid emulsions. Because isolation of this fungus requires special culture techniques, which are not routinely used, the authors of many case reports of M. furfur infections in adults question whether infections caused by this organism are being underdiagnosed in older patients. Methods: Catheter insertion site colonization rates in adults receiving total parenteral nutrition (TPN) were prospectively evaluated in 149 hospitalized patients with 928 cultures handled specifically for M. furfur detection. Positive control samples consisted of M. furfur cultures in neonates and in adults, who had not been enrolled in the study, and of a separate positive culture obtained from a skin site inoculated with M. furfur. Results: M. furfur was not cultured from any of the 928 study samples (95% confidence interval [CI] -0.4% to +0.4%). Conclusions: These results suggest that M. furfur less of a threat to hospitalized adults receiving TPN than has been otherwise postulated. These data do not support the inclusion of special cultures for M. furfur in routine skin-site surveillance programs among hospitalized adults receiving TPN.

Original languageEnglish (US)
Pages (from-to)230-232
Number of pages3
JournalJournal of Parenteral and Enteral Nutrition
Volume21
Issue number4
StatePublished - Jul 1997
Externally publishedYes

Fingerprint

Malassezia furfur
Malassezia
Total Parenteral Nutrition
total parenteral nutrition
Skin
pathogens
neonates
Newborn Infant
case studies
Culture Techniques
Surveys and Questionnaires
Infection
Emulsions
catheters
infection
emulsions
confidence interval
Fungi
Catheters
Confidence Intervals

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

A prospective survey for central line skin-site colonization by the pathogen Malassezia furfur among hospitalized adults receiving total parenteral nutrition. / Jatoi, Aminah; Hanjosten, Karen; Ross, Elizabeth; Mason, Joel B.

In: Journal of Parenteral and Enteral Nutrition, Vol. 21, No. 4, 07.1997, p. 230-232.

Research output: Contribution to journalArticle

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