A proposal for standardized grading of chronic changes in native kidney biopsy specimens

Sanjeev Sethi, Vivette D. D'Agati, Cynthia C. Nast, Agnes B. Fogo, An S. De Vriese, Glen S. Markowitz, Richard J. Glassock, Fernando C. Fervenza, Surya V. Seshan, Andrew Rule, Lorraine C. Racusen, Jai Radhakrishnan, Christopher G. Winearls, Gerald B. Appel, Ingeborg M. Bajema, Anthony Chang, Robert B. Colvin, H. Terence Cook, Sundaram Hariharan, Loren P. Herrera HernandezNeeraja Kambham, Michael Mengel, Karl A. Nath, Helmut G. Rennke, Pierre Ronco, Brad H. Rovin, Mark Haas

Research output: Contribution to journalArticlepeer-review

46 Scopus citations

Abstract

Chronic changes represent an important component of native kidney biopsy evaluation and have a major bearing on predicting prognosis and guiding treatment. We propose here a uniform, semiquantitative approach to assessing such changes, which include glomerulosclerosis, tubular atrophy, interstitial fibrosis, and arteriosclerosis, and we report these findings as an overall chronicity grade.

Original languageEnglish (US)
Pages (from-to)787-789
Number of pages3
JournalKidney international
Volume91
Issue number4
DOIs
StatePublished - Apr 1 2017

Keywords

  • arteriosclerosis
  • glomerulosclerosis
  • interstitial fibrosis
  • native kidney biopsy
  • tubular atrophy

ASJC Scopus subject areas

  • Nephrology

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