A practical approach to the diagnosis of spinal cord lesions

Romina Mariano, Eoin Flanagan, Brian G Weinshenker, Jacqueline Palace

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

Every neurologist will be familiar with the patient with atypical spinal cord disease and the challenges of taking the diagnosis forward. This is predominantly because of the limited range of possible clinical and investigation findings making most individual features non-specific. The difficulty in obtaining a tissue diagnosis further contributes and patients are often treated empirically based on local prevalence and potential for reversibility. This article focuses on improving the diagnosis of adult non-traumatic, non-compressive spinal cord disorders. It is structured to start with the clinical presentation in order to be of practical use to the clinician. We aim, by combining the onset phenotype with the subsequent course, along with imaging and laboratory features, to improve the diagnostic process.

Original languageEnglish (US)
Pages (from-to)187-200
Number of pages14
JournalPractical Neurology
Volume18
Issue number3
DOIs
StatePublished - Jun 1 2018

Fingerprint

Spinal Cord
Spinal Cord Diseases
Phenotype
Neurologists

Keywords

  • clinical neurology
  • MRI
  • myelopathy

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

A practical approach to the diagnosis of spinal cord lesions. / Mariano, Romina; Flanagan, Eoin; Weinshenker, Brian G; Palace, Jacqueline.

In: Practical Neurology, Vol. 18, No. 3, 01.06.2018, p. 187-200.

Research output: Contribution to journalReview article

Mariano, Romina ; Flanagan, Eoin ; Weinshenker, Brian G ; Palace, Jacqueline. / A practical approach to the diagnosis of spinal cord lesions. In: Practical Neurology. 2018 ; Vol. 18, No. 3. pp. 187-200.
@article{f2cd3f2fcf0e466c95363a4da4db6fc3,
title = "A practical approach to the diagnosis of spinal cord lesions",
abstract = "Every neurologist will be familiar with the patient with atypical spinal cord disease and the challenges of taking the diagnosis forward. This is predominantly because of the limited range of possible clinical and investigation findings making most individual features non-specific. The difficulty in obtaining a tissue diagnosis further contributes and patients are often treated empirically based on local prevalence and potential for reversibility. This article focuses on improving the diagnosis of adult non-traumatic, non-compressive spinal cord disorders. It is structured to start with the clinical presentation in order to be of practical use to the clinician. We aim, by combining the onset phenotype with the subsequent course, along with imaging and laboratory features, to improve the diagnostic process.",
keywords = "clinical neurology, MRI, myelopathy",
author = "Romina Mariano and Eoin Flanagan and Weinshenker, {Brian G} and Jacqueline Palace",
year = "2018",
month = "6",
day = "1",
doi = "10.1136/practneurol-2017-001845",
language = "English (US)",
volume = "18",
pages = "187--200",
journal = "Practical Neurology",
issn = "1474-7758",
publisher = "BMJ Publishing Group",
number = "3",

}

TY - JOUR

T1 - A practical approach to the diagnosis of spinal cord lesions

AU - Mariano, Romina

AU - Flanagan, Eoin

AU - Weinshenker, Brian G

AU - Palace, Jacqueline

PY - 2018/6/1

Y1 - 2018/6/1

N2 - Every neurologist will be familiar with the patient with atypical spinal cord disease and the challenges of taking the diagnosis forward. This is predominantly because of the limited range of possible clinical and investigation findings making most individual features non-specific. The difficulty in obtaining a tissue diagnosis further contributes and patients are often treated empirically based on local prevalence and potential for reversibility. This article focuses on improving the diagnosis of adult non-traumatic, non-compressive spinal cord disorders. It is structured to start with the clinical presentation in order to be of practical use to the clinician. We aim, by combining the onset phenotype with the subsequent course, along with imaging and laboratory features, to improve the diagnostic process.

AB - Every neurologist will be familiar with the patient with atypical spinal cord disease and the challenges of taking the diagnosis forward. This is predominantly because of the limited range of possible clinical and investigation findings making most individual features non-specific. The difficulty in obtaining a tissue diagnosis further contributes and patients are often treated empirically based on local prevalence and potential for reversibility. This article focuses on improving the diagnosis of adult non-traumatic, non-compressive spinal cord disorders. It is structured to start with the clinical presentation in order to be of practical use to the clinician. We aim, by combining the onset phenotype with the subsequent course, along with imaging and laboratory features, to improve the diagnostic process.

KW - clinical neurology

KW - MRI

KW - myelopathy

UR - http://www.scopus.com/inward/record.url?scp=85053378818&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85053378818&partnerID=8YFLogxK

U2 - 10.1136/practneurol-2017-001845

DO - 10.1136/practneurol-2017-001845

M3 - Review article

C2 - 29500319

AN - SCOPUS:85053378818

VL - 18

SP - 187

EP - 200

JO - Practical Neurology

JF - Practical Neurology

SN - 1474-7758

IS - 3

ER -