A post-processing technique to suppress fluid signal and increase contrast in multispectral MR exams of MS patients

J. R. Mitchell, P. Gareau, S. Karlik, B. Rutt

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

We present a new method to extract data from multispectral MR exams of patients with Multiple Sclerosis. Our technique produces images of “spectral phase” relative to cerebro-spinal fluid (CSF-SP images). It provides a convenient way of reducing multispectral MR exams to a single, intuitive image with contrast characteristics similar to anatomical photographs. Our new images provide better tissue contrast than that found in any of the MR images. Contrast between CSF and white matter (WM) was increased from a maximum of 19.5 in the T1w MR image to 56 in the CSF-SP image (+187%). Contrast between CSF and gray matter (GM) increased from a maximum of 14.5 in the T1w image to 35.2 in the CSF-SP image (+143%). Finally, contrast between WM and GM increased from a maximum of 7.5 in the T2w image to 11.5 in the CSF-SP image (+53%). The additional contrast in CSF-SP images may aid the quantification and analysis of lesion activity in MR exams of MS patients.

Original languageEnglish (US)
Title of host publicationMedical Image Computing and Computer-Assisted Intervention –MICCAI 1999 - 2nd International Conference, Proceedings
EditorsChris Taylor, Alain Colchester
PublisherSpringer Verlag
Pages218-226
Number of pages9
ISBN (Print)354066503X, 9783540665038
DOIs
StatePublished - 1999
Event2nd International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 1999 - Cambridge, United Kingdom
Duration: Sep 19 1999Sep 22 1999

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume1679
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other2nd International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 1999
CountryUnited Kingdom
CityCambridge
Period9/19/999/22/99

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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