A pilot randomized trial of two cognitive rehabilitation interventions for mild cognitive impairment: caregiver outcomes

Andrea V. Cuc, Dona E.C. Locke, Noah Duncan, Julie A. Fields, Charlene Hoffman Snyder, Sherrie Hanna, Angela Lunde, Glenn E. Smith, Melanie Chandler

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Objective: This study aims to provide effect size estimates of the impact of two cognitive rehabilitation interventions provided to patients with mild cognitive impairment: computerized brain fitness exercise and memory support system on support partners' outcomes of depression, anxiety, quality of life, and partner burden. Methods: A randomized controlled pilot trial was performed. Results: At 6 months, the partners from both treatment groups showed stable to improved depression scores, while partners in an untreated control group showed worsening depression over 6 months. There were no statistically significant differences on anxiety, quality of life, or burden outcomes in this small pilot trial; however, effect sizes were moderate, suggesting that the sample sizes in this pilot study were not adequate to detect statistical significance. Conclusion: Either form of cognitive rehabilitation may help partners' mood, compared with providing no treatment. However, effect size estimates related to other partner outcomes (i.e., burden, quality of life, and anxiety) suggest that follow-up efficacy trials will need sample sizes of at least 30–100 people per group to accurately determine significance.

Original languageEnglish (US)
Pages (from-to)e180-e187
JournalInternational Journal of Geriatric Psychiatry
Volume32
Issue number12
DOIs
StatePublished - Dec 2017

Keywords

  • behavioral intervention
  • caregivers
  • cognitive rehabilitation
  • mild cognitive impairment

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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