A pessimistic explanatory style is prognostic for poor lung cancer survival

Paul Novotny, Robert C. Colligan, Daniel W. Szydlo, Matthew M Clark, Sarah Rausch, Jason Wampfler, Jeff A Sloan, Ping Yang

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Background: Several studies have demonstrated the importance of personality constructs on health behaviors and health status. Having a pessimistic outlook has been related to negative health behaviors and higher mortality. However, the construct has not been well explored in cancer populations. Methods: Survival time of 534 adults who were diagnosed with lung cancer was examined. The patients had completed the Minnesota Multiphasic Personality Inventory approximately 18.2 years before receiving their lung cancer diagnosis. Minnesota Multiphasic Personality Inventory Optimism-Pessimism scores were divided into high (60 or more) and low scores (<60), and log-rank tests and Kaplan-Meier curves were used to determine survival differences. Multivariate Cox models were used for assessing prognostic values of pessimism along with other known predictors for lung cancer survival outcome. Bootstrapping of the survival models was used as a sensitivity analysis. Results: At the time of lung cancer diagnosis, patients were at an average age of 67 years old; 48% of them were women, 85% had non-small cell lung cancer, 15% had small cell lung cancer, 30% were stage I, 4% were stage II, 31% were stage III/limited, and 35% were stage IV/extensive. Patients who exhibited a nonpessimistic explanatory style survived approximately 6 months longer than patients classified as having a pessimistic explanatory style. Conclusion: Among lung cancer patients, those having a pessimistic explanatory style experienced a less favorable survival outcome, which may be related to cancer treatment decisions. Further research in this area is warranted.

Original languageEnglish (US)
Pages (from-to)326-332
Number of pages7
JournalJournal of Thoracic Oncology
Volume5
Issue number3
DOIs
StatePublished - Mar 2010

Fingerprint

Lung Neoplasms
Survival
MMPI
Health Behavior
Second Primary Neoplasms
Small Cell Lung Carcinoma
Kaplan-Meier Estimate
Proportional Hazards Models
Non-Small Cell Lung Carcinoma
Health Status
Personality
Mortality
Research
Population
Neoplasms
Pessimism

Keywords

  • Explanatory style
  • Lung cancer
  • MMPI
  • Optimism
  • Pessimism
  • Survival

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine

Cite this

A pessimistic explanatory style is prognostic for poor lung cancer survival. / Novotny, Paul; Colligan, Robert C.; Szydlo, Daniel W.; Clark, Matthew M; Rausch, Sarah; Wampfler, Jason; Sloan, Jeff A; Yang, Ping.

In: Journal of Thoracic Oncology, Vol. 5, No. 3, 03.2010, p. 326-332.

Research output: Contribution to journalArticle

Novotny, Paul ; Colligan, Robert C. ; Szydlo, Daniel W. ; Clark, Matthew M ; Rausch, Sarah ; Wampfler, Jason ; Sloan, Jeff A ; Yang, Ping. / A pessimistic explanatory style is prognostic for poor lung cancer survival. In: Journal of Thoracic Oncology. 2010 ; Vol. 5, No. 3. pp. 326-332.
@article{80030ca4e7f443708846ce912c377e6f,
title = "A pessimistic explanatory style is prognostic for poor lung cancer survival",
abstract = "Background: Several studies have demonstrated the importance of personality constructs on health behaviors and health status. Having a pessimistic outlook has been related to negative health behaviors and higher mortality. However, the construct has not been well explored in cancer populations. Methods: Survival time of 534 adults who were diagnosed with lung cancer was examined. The patients had completed the Minnesota Multiphasic Personality Inventory approximately 18.2 years before receiving their lung cancer diagnosis. Minnesota Multiphasic Personality Inventory Optimism-Pessimism scores were divided into high (60 or more) and low scores (<60), and log-rank tests and Kaplan-Meier curves were used to determine survival differences. Multivariate Cox models were used for assessing prognostic values of pessimism along with other known predictors for lung cancer survival outcome. Bootstrapping of the survival models was used as a sensitivity analysis. Results: At the time of lung cancer diagnosis, patients were at an average age of 67 years old; 48{\%} of them were women, 85{\%} had non-small cell lung cancer, 15{\%} had small cell lung cancer, 30{\%} were stage I, 4{\%} were stage II, 31{\%} were stage III/limited, and 35{\%} were stage IV/extensive. Patients who exhibited a nonpessimistic explanatory style survived approximately 6 months longer than patients classified as having a pessimistic explanatory style. Conclusion: Among lung cancer patients, those having a pessimistic explanatory style experienced a less favorable survival outcome, which may be related to cancer treatment decisions. Further research in this area is warranted.",
keywords = "Explanatory style, Lung cancer, MMPI, Optimism, Pessimism, Survival",
author = "Paul Novotny and Colligan, {Robert C.} and Szydlo, {Daniel W.} and Clark, {Matthew M} and Sarah Rausch and Jason Wampfler and Sloan, {Jeff A} and Ping Yang",
year = "2010",
month = "3",
doi = "10.1097/JTO.0b013e3181ce70e8",
language = "English (US)",
volume = "5",
pages = "326--332",
journal = "Journal of Thoracic Oncology",
issn = "1556-0864",
publisher = "International Association for the Study of Lung Cancer",
number = "3",

}

TY - JOUR

T1 - A pessimistic explanatory style is prognostic for poor lung cancer survival

AU - Novotny, Paul

AU - Colligan, Robert C.

AU - Szydlo, Daniel W.

AU - Clark, Matthew M

AU - Rausch, Sarah

AU - Wampfler, Jason

AU - Sloan, Jeff A

AU - Yang, Ping

PY - 2010/3

Y1 - 2010/3

N2 - Background: Several studies have demonstrated the importance of personality constructs on health behaviors and health status. Having a pessimistic outlook has been related to negative health behaviors and higher mortality. However, the construct has not been well explored in cancer populations. Methods: Survival time of 534 adults who were diagnosed with lung cancer was examined. The patients had completed the Minnesota Multiphasic Personality Inventory approximately 18.2 years before receiving their lung cancer diagnosis. Minnesota Multiphasic Personality Inventory Optimism-Pessimism scores were divided into high (60 or more) and low scores (<60), and log-rank tests and Kaplan-Meier curves were used to determine survival differences. Multivariate Cox models were used for assessing prognostic values of pessimism along with other known predictors for lung cancer survival outcome. Bootstrapping of the survival models was used as a sensitivity analysis. Results: At the time of lung cancer diagnosis, patients were at an average age of 67 years old; 48% of them were women, 85% had non-small cell lung cancer, 15% had small cell lung cancer, 30% were stage I, 4% were stage II, 31% were stage III/limited, and 35% were stage IV/extensive. Patients who exhibited a nonpessimistic explanatory style survived approximately 6 months longer than patients classified as having a pessimistic explanatory style. Conclusion: Among lung cancer patients, those having a pessimistic explanatory style experienced a less favorable survival outcome, which may be related to cancer treatment decisions. Further research in this area is warranted.

AB - Background: Several studies have demonstrated the importance of personality constructs on health behaviors and health status. Having a pessimistic outlook has been related to negative health behaviors and higher mortality. However, the construct has not been well explored in cancer populations. Methods: Survival time of 534 adults who were diagnosed with lung cancer was examined. The patients had completed the Minnesota Multiphasic Personality Inventory approximately 18.2 years before receiving their lung cancer diagnosis. Minnesota Multiphasic Personality Inventory Optimism-Pessimism scores were divided into high (60 or more) and low scores (<60), and log-rank tests and Kaplan-Meier curves were used to determine survival differences. Multivariate Cox models were used for assessing prognostic values of pessimism along with other known predictors for lung cancer survival outcome. Bootstrapping of the survival models was used as a sensitivity analysis. Results: At the time of lung cancer diagnosis, patients were at an average age of 67 years old; 48% of them were women, 85% had non-small cell lung cancer, 15% had small cell lung cancer, 30% were stage I, 4% were stage II, 31% were stage III/limited, and 35% were stage IV/extensive. Patients who exhibited a nonpessimistic explanatory style survived approximately 6 months longer than patients classified as having a pessimistic explanatory style. Conclusion: Among lung cancer patients, those having a pessimistic explanatory style experienced a less favorable survival outcome, which may be related to cancer treatment decisions. Further research in this area is warranted.

KW - Explanatory style

KW - Lung cancer

KW - MMPI

KW - Optimism

KW - Pessimism

KW - Survival

UR - http://www.scopus.com/inward/record.url?scp=77649276961&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77649276961&partnerID=8YFLogxK

U2 - 10.1097/JTO.0b013e3181ce70e8

DO - 10.1097/JTO.0b013e3181ce70e8

M3 - Article

C2 - 20139778

AN - SCOPUS:77649276961

VL - 5

SP - 326

EP - 332

JO - Journal of Thoracic Oncology

JF - Journal of Thoracic Oncology

SN - 1556-0864

IS - 3

ER -