TY - JOUR
T1 - A novel vitamin D-regulated immediate-early gene, IEX-1, alters cellular growth and apoptosis.
AU - Kumar, Rajiv
AU - Pittelkow, Mark R.
AU - Salisbury, Jeffrey L.
AU - Grande, Joseph P.
AU - Im, Hee Jeong
AU - Feldmann, Kathrin A.
AU - Schilling, David
PY - 2003
Y1 - 2003
N2 - 1alpha,25-Dihydroxyvitamin D3 (1alpha,25(OH)2D3) inhibits the expression of an immediate-early gene, IEX-1, which is involved in the regulation of cellular growth and apoptosis in a variety of cells. 1alpha,25(OH)2D3 alters the subcellular localization of IEX-1 by causing an efflux of IEX-1 from the nucleus, and the sterol decreases the expression of IEX-1 messenger RNA in cells via a novel DR3 repeat-type DNA response element.
AB - 1alpha,25-Dihydroxyvitamin D3 (1alpha,25(OH)2D3) inhibits the expression of an immediate-early gene, IEX-1, which is involved in the regulation of cellular growth and apoptosis in a variety of cells. 1alpha,25(OH)2D3 alters the subcellular localization of IEX-1 by causing an efflux of IEX-1 from the nucleus, and the sterol decreases the expression of IEX-1 messenger RNA in cells via a novel DR3 repeat-type DNA response element.
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U2 - 10.1007/978-3-642-55580-0_8
DO - 10.1007/978-3-642-55580-0_8
M3 - Review article
C2 - 12899517
AN - SCOPUS:0642275430
SN - 0080-0015
VL - 164
SP - 123
EP - 134
JO - Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer
JF - Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer
ER -