A novel technique—Prophylactic septal radiofrequency ablation to prevent left ventricular outflow tract obstruction with transcatheter mitral valve replacement (RADIO-TMVR)

Ammar M. Killu, Mayra Guerrero, Konstantinos C. Siontis, Abdallah El Sabbagh, Mackram F. Eleid, Mohamad Alkhouli, Charanjit Rihal, Samuel J. Asirvatham

Research output: Contribution to journalArticlepeer-review

Abstract

Transcatheter mitral valve replacement (TMVR) with off-label use of aortic balloon-expandable transcatheter heart valves has emerged as a therapeutic option in high-surgical risk patients with severe mitral annular calcification. Left ventricular outflow tract (LVOT) obstruction post valve deployment is a major limitation. We describe a case of septal reduction therapy using radiofrequency ablation (RFA) when established methods of septal reduction were either ineffective or not feasible. RFA permitted successful enlargement of the LVOT area and subsequent TMVR.

Original languageEnglish (US)
Pages (from-to)3048-3055
Number of pages8
JournalJournal of cardiovascular electrophysiology
Volume31
Issue number11
DOIs
StatePublished - Nov 1 2020

Keywords

  • HCM
  • LVOT obstruction
  • ablation
  • hypertrophy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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