A novel MRI texture analysis of demyelination and inflammation in relapsing-remitting experimental allergic encephalomyelitis

Yunyan Zhang; Jennifer Wells; Richard Buist; James Peeling; V. Wee Yong; Joseph Ross Mitchell

A novel MRI texture analysis of demyelination and inflammation in relapsing-remitting experimental allergic encephalomyelitis

Yunyan Zhang, Jennifer Wells, Richard Buist, James Peeling, V. Wee Yong, Joseph Ross Mitchell

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We have developed a novel multiscale localized image texture analysis technique, based upon the polar Stockwell Transform (PST). In this paper we characterized image texture in vivo using the PST in historically verified lesion areas in T2-weighted MRI of an animal model of multiple sclerosis. Both high and low frequency signals, representing inflammation and demyelination, were significantly increased in pathological regions compared to normal control tissue. This suggests that this new local spatial-frequency measure of image texture may provide a sensitive and precise indication of disease activity.

Original language	English (US)
Title of host publication	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Pages	760-767
Number of pages	8
Volume	4190 LNCS - I
State	Published - 2006
Externally published	Yes
Event	9th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2006 - Copenhagen, Denmark Duration: Oct 1 2006 → Oct 6 2006

Publication series

Name	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume	4190 LNCS - I
ISSN (Print)	03029743
ISSN (Electronic)	16113349

Other

Other	9th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2006
Country/Territory	Denmark
City	Copenhagen
Period	10/1/06 → 10/6/06

ASJC Scopus subject areas

General Computer Science
General Biochemistry, Genetics and Molecular Biology
Theoretical Computer Science

Cite this

Zhang, Y., Wells, J., Buist, R., Peeling, J., Yong, V. W., & Mitchell, J. R. (2006). A novel MRI texture analysis of demyelination and inflammation in relapsing-remitting experimental allergic encephalomyelitis. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 4190 LNCS - I, pp. 760-767). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 4190 LNCS - I).

A novel MRI texture analysis of demyelination and inflammation in relapsing-remitting experimental allergic encephalomyelitis. / Zhang, Yunyan; Wells, Jennifer; Buist, Richard et al.
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Vol. 4190 LNCS - I 2006. p. 760-767 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 4190 LNCS - I).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Zhang, Y, Wells, J, Buist, R, Peeling, J, Yong, VW & Mitchell, JR 2006, A novel MRI texture analysis of demyelination and inflammation in relapsing-remitting experimental allergic encephalomyelitis. in Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). vol. 4190 LNCS - I, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 4190 LNCS - I, pp. 760-767, 9th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2006, Copenhagen, Denmark, 10/1/06.

Zhang Y, Wells J, Buist R, Peeling J, Yong VW, Mitchell JR. A novel MRI texture analysis of demyelination and inflammation in relapsing-remitting experimental allergic encephalomyelitis. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Vol. 4190 LNCS - I. 2006. p. 760-767. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)).

Zhang, Yunyan ; Wells, Jennifer ; Buist, Richard et al. / A novel MRI texture analysis of demyelination and inflammation in relapsing-remitting experimental allergic encephalomyelitis. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Vol. 4190 LNCS - I 2006. pp. 760-767 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)).

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A novel MRI texture analysis of demyelination and inflammation in relapsing-remitting experimental allergic encephalomyelitis

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