A Novel Missense (M206K) STAT3 Mutation in Diffuse Large B Cell Lymphoma Deregulates STAT3 Signaling

Agriculture & Biology

• B-cell lymphoma 100%
• B-lymphocytes 54%
• mutation 47%
• neoplasms 42%
• mutants 32%
• cell lines 30%
• point mutation 30%
• codons 26%
• exons 24%
• missense mutation 18%
• cells 17%
• luciferase 15%
• transcriptional activation 15%
• stop codon 15%
• transfection 15%
• site-directed mutagenesis 14%
• phosphorylation 12%
• methionine 11%
• lysine 11%
• plasmids 10%
• assays 7%
• genes 4%

Medicine & Life Sciences

• Lymphoma, Large B-Cell, Diffuse 77%
• B-Lymphocytes 53%
• Mutation 38%
• Codon 34%
• Point Mutation 33%
• Cell Line 30%
• Exons 28%
• Silent Mutation 23%
• Neoplasms 22%
• Terminator Codon 20%
• Site-Directed Mutagenesis 18%
• Methionine 17%
• Missense Mutation 17%
• Lysine 16%
• Luciferases 16%
• Transcriptional Activation 15%
• Transfection 14%
• Plasmids 13%
• Phosphorylation 11%
• Genes 6%

Chemical Compounds

• Mutation 58%
• Site-Directed Mutagenesis 8%
• Methionine 8%
• Lysine 8%
• Substitution Reaction 5%