A novel design to power the micro-ECG sensor implanted in adult zebrafish

Daniel Schossow, Peter Ritchie, Hung Cao, J. C. Chiao, Jingchun Yang, Xiaolei H Xu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Heart diseases have been the leading cause of death in the developed world, partially due to failure to adequately replace lost ventricular myocardium from ischemia-induced infarct. Adult mammalian ventricular cardiomyocytes have a limited capacity to divide, and this proliferation is insufficient to overcome the significant loss of myocardium from ventricular injury. Unlike mammalian hearts, zebrafish (Danio rerio) hearts fully regenerate after 20% ventricular amputation in 2 months, thereby providing a genetically tractable model system for heart regeneration investigations. Recently, electrocardiogram (ECG) assessment in zebrafish has showed promise as an alternative method to study heart regeneration and heart diseases; however, all existing approaches involving the use of anesthesia drugs are inadequate to provide intrinsic ECG signals. Towards a wireless ECG platform, we use the wireless power transfer (WPT) technique via inductive coupling to power an ECG sensor implanted in an adult zebrafish. The transmitter coil is a solenoid wound around a customized cylindrical housing while the compact receiver solenoid on the fish is modified to counter misalignment issues. The ECG data are sent to the external unit via backscattering in the form of load modulation using the same inductive link. Our system enables continuous monitoring of freely-swimming fish without disrupting their normal activities. An adaptive tuning method is used and power transfer efficiency (PTE) is characterized using a vector network analyzer (VNA) via S-parameter measurement.

Original languageEnglish (US)
Title of host publication2017 IEEE Antennas and Propagation Society International Symposium, Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1681-1682
Number of pages2
Volume2017-January
ISBN (Electronic)9781538632840
DOIs
StatePublished - Oct 18 2017
Event2017 IEEE International Symposium on Antennas and Propagation and USNC-URSI Radio Science Meeting, APSURSI 2017 - San Diego, United States
Duration: Jul 9 2017Jul 14 2017

Other

Other2017 IEEE International Symposium on Antennas and Propagation and USNC-URSI Radio Science Meeting, APSURSI 2017
CountryUnited States
CitySan Diego
Period7/9/177/14/17

Fingerprint

electrocardiography
Electrocardiography
sensors
Sensors
heart diseases
myocardium
fishes
solenoids
regeneration
Solenoids
Fish
anesthesia
ischemia
disrupting
Electric network analyzers
death
misalignment
transmitters
Scattering parameters
Backscattering

Keywords

  • ECG
  • Heart regeneration
  • Inductive coupling
  • Wireless power transfer
  • Zebrafish

ASJC Scopus subject areas

  • Radiation
  • Computer Networks and Communications
  • Instrumentation

Cite this

Schossow, D., Ritchie, P., Cao, H., Chiao, J. C., Yang, J., & Xu, X. H. (2017). A novel design to power the micro-ECG sensor implanted in adult zebrafish. In 2017 IEEE Antennas and Propagation Society International Symposium, Proceedings (Vol. 2017-January, pp. 1681-1682). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/APUSNCURSINRSM.2017.8072883

A novel design to power the micro-ECG sensor implanted in adult zebrafish. / Schossow, Daniel; Ritchie, Peter; Cao, Hung; Chiao, J. C.; Yang, Jingchun; Xu, Xiaolei H.

2017 IEEE Antennas and Propagation Society International Symposium, Proceedings. Vol. 2017-January Institute of Electrical and Electronics Engineers Inc., 2017. p. 1681-1682.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Schossow, D, Ritchie, P, Cao, H, Chiao, JC, Yang, J & Xu, XH 2017, A novel design to power the micro-ECG sensor implanted in adult zebrafish. in 2017 IEEE Antennas and Propagation Society International Symposium, Proceedings. vol. 2017-January, Institute of Electrical and Electronics Engineers Inc., pp. 1681-1682, 2017 IEEE International Symposium on Antennas and Propagation and USNC-URSI Radio Science Meeting, APSURSI 2017, San Diego, United States, 7/9/17. https://doi.org/10.1109/APUSNCURSINRSM.2017.8072883
Schossow D, Ritchie P, Cao H, Chiao JC, Yang J, Xu XH. A novel design to power the micro-ECG sensor implanted in adult zebrafish. In 2017 IEEE Antennas and Propagation Society International Symposium, Proceedings. Vol. 2017-January. Institute of Electrical and Electronics Engineers Inc. 2017. p. 1681-1682 https://doi.org/10.1109/APUSNCURSINRSM.2017.8072883
Schossow, Daniel ; Ritchie, Peter ; Cao, Hung ; Chiao, J. C. ; Yang, Jingchun ; Xu, Xiaolei H. / A novel design to power the micro-ECG sensor implanted in adult zebrafish. 2017 IEEE Antennas and Propagation Society International Symposium, Proceedings. Vol. 2017-January Institute of Electrical and Electronics Engineers Inc., 2017. pp. 1681-1682
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