Abstract
Introduction: This study established the psychometric properties and preliminary validity of the Stricker Learning Span (SLS), a novel computer adaptive word list memory test designed for remote assessment and optimized for smartphone use. Methods: Women enrolled in the Mayo Clinic Specialized Center of Research Excellence (SCORE) were recruited via e-mail or phone to complete two remote cognitive testing sessions. Convergent validity was assessed through correlation with previously administered in-person neuropsychological tests (n = 96, ages 55–79) and criterion validity through associations with magnetic resonance imaging measures of neurodegeneration sensitive to Alzheimer's disease (n = 47). Results: SLS performance significantly correlated with the Auditory Verbal Learning Test and measures of neurodegeneration (temporal meta-regions of interest and entorhinal cortical thickness, adjusting for age and education). Test–retest reliabilities across two sessions were 0.71–0.76 (two-way mixed intraclass correlation coefficients). Discussion: The SLS is a valid and reliable self-administered memory test that shows promise for remote assessment of aging and neurodegenerative disorders.
Original language | English (US) |
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Article number | e12299 |
Journal | Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring |
Volume | 14 |
Issue number | 1 |
DOIs | |
State | Published - 2022 |
Keywords
- Alzheimer's disease
- Mayo Test Drive
- Stricker Learning Span
- Symbols Test
- aging
- cortical thickness
- entorhinal cortex
- hippocampus
- learning
- mobile health
- reliability
- smartphone
- validity
- web
ASJC Scopus subject areas
- Clinical Neurology
- Psychiatry and Mental health