TY - JOUR
T1 - A new socioeconomic status measure for vaccine research in children using individual housing data
T2 - A population-based case-control study
AU - Hammer, Rachel
AU - Capili, Conrad
AU - Wi, Chung Il
AU - Ryu, Euijung
AU - Rand-Weaver, Jennifer
AU - Juhn, Young J.
N1 - Funding Information:
Rochester, Minnesota, is centrally located in Olmsted County. During the study period, characteristics of the City of Rochester and Olmsted County populations were similar to those of the U.S. Caucasian population, with the exception of a higher proportion of the working population employed in the health care industry [26]. Health care in Olmsted County, Minnesota, is virtually self-contained within the community. Uniquely, when patients first register care with any health care provider in the community, they are asked to authorize the use of their medical records for research. Those who grant such authorization (and 95 % do), are assigned a unique identifier with the Rochester Epidemiology Project (REP), a program which has been continuously funded by the NIH since 1966. All clinical diagnoses and information from every episode of care are contained within detailed patient-based medical records. This unique longitudinal population-based resource has been the source of over 2000 publications on the epidemiology of disease.
Funding Information:
This work was supported by the National Institute of Allergy and Infectious Diseases (R21 AI101277), the Scholarly Clinician Award from the Mayo Foundation, and the Division of Community Pediatric and Adolescent Medicine, Mayo Clinic. Also, this study was made possible using the resources of the Rochester Epidemiology Project, which is supported by the National Institute on Aging of the National Institutes of Health under Award Number R01AG034676.
Publisher Copyright:
© 2016 The Author(s).
PY - 2016/9/21
Y1 - 2016/9/21
N2 - Background: We recently developed HOUSES, an individual housing-based socioeconomic status (SES) measurement for health disparities research. We assessed whether HOUSES was associated with risk of pertussis and pertussis vaccine up-to-date status in children. Methods: The study utilized a previous population-based case-control study cohort assembled during the 2004-2005 pertussis outbreak. We collected data on pertussis vaccine status (up-to-date status) at the time of the index date. Using a z-score for housing value, actual square footage, and numbers of bedrooms and bathrooms, HOUSES was formulated in continuous variable and categorized into quartiles. Vaccine up-to-date status was compared among subjects with different SES as measured by HOUSES using a chi-square test and logistic regression models. Results: Of the 391 eligible pediatric subjects (median age of 13.1 years with male sex of 55 %), 363 (93 %) were successfully geocoded to formulate HOUSES index. HOUSES was not associated with the risk of pertussis (p = 0.82). Pertussis vaccine up-to-date statuses were 79, 86, 83, and 94 % for children in the first (the lowest SES), second, third, and fourth quartiles of HOUSES, respectively (p = 0.03). HOUSES as a continuous variable was associated with pertussis vaccine up-to-date status (adjusted OR: 1.15 per increment of one unit of HOUSES, 95 % CI: 1.04-1.27, p = 0.008). Conclusion: While HOUSES is not associated with the risk of pertussis, it predicts vaccine up-to-date status among children with different SES. HOUSES may be a useful tool for vaccine delivery research among children.
AB - Background: We recently developed HOUSES, an individual housing-based socioeconomic status (SES) measurement for health disparities research. We assessed whether HOUSES was associated with risk of pertussis and pertussis vaccine up-to-date status in children. Methods: The study utilized a previous population-based case-control study cohort assembled during the 2004-2005 pertussis outbreak. We collected data on pertussis vaccine status (up-to-date status) at the time of the index date. Using a z-score for housing value, actual square footage, and numbers of bedrooms and bathrooms, HOUSES was formulated in continuous variable and categorized into quartiles. Vaccine up-to-date status was compared among subjects with different SES as measured by HOUSES using a chi-square test and logistic regression models. Results: Of the 391 eligible pediatric subjects (median age of 13.1 years with male sex of 55 %), 363 (93 %) were successfully geocoded to formulate HOUSES index. HOUSES was not associated with the risk of pertussis (p = 0.82). Pertussis vaccine up-to-date statuses were 79, 86, 83, and 94 % for children in the first (the lowest SES), second, third, and fourth quartiles of HOUSES, respectively (p = 0.03). HOUSES as a continuous variable was associated with pertussis vaccine up-to-date status (adjusted OR: 1.15 per increment of one unit of HOUSES, 95 % CI: 1.04-1.27, p = 0.008). Conclusion: While HOUSES is not associated with the risk of pertussis, it predicts vaccine up-to-date status among children with different SES. HOUSES may be a useful tool for vaccine delivery research among children.
KW - Epidemiology
KW - Socioeconomic status
KW - Vaccination
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U2 - 10.1186/s12889-016-3673-x
DO - 10.1186/s12889-016-3673-x
M3 - Article
AN - SCOPUS:84989848923
VL - 16
JO - BMC Public Health
JF - BMC Public Health
SN - 1471-2458
IS - 1
M1 - 1000
ER -