TY - JOUR
T1 - A new socioeconomic status measure for vaccine research in children using individual housing data
T2 - A population-based case-control study
AU - Hammer, Rachel
AU - Capili, Conrad
AU - Wi, Chung Il
AU - Ryu, Euijung
AU - Rand-Weaver, Jennifer
AU - Juhn, Young J.
N1 - Funding Information:
This work was supported by the National Institute of Allergy and Infectious Diseases (R21 AI101277), the Scholarly Clinician Award from the Mayo Foundation, and the Division of Community Pediatric and Adolescent Medicine, Mayo Clinic. Also, this study was made possible using the resources of the Rochester Epidemiology Project, which is supported by the National Institute on Aging of the National Institutes of Health under Award Number R01AG034676.
PY - 2016/9/21
Y1 - 2016/9/21
N2 - Background: We recently developed HOUSES, an individual housing-based socioeconomic status (SES) measurement for health disparities research. We assessed whether HOUSES was associated with risk of pertussis and pertussis vaccine up-to-date status in children. Methods: The study utilized a previous population-based case-control study cohort assembled during the 2004-2005 pertussis outbreak. We collected data on pertussis vaccine status (up-to-date status) at the time of the index date. Using a z-score for housing value, actual square footage, and numbers of bedrooms and bathrooms, HOUSES was formulated in continuous variable and categorized into quartiles. Vaccine up-to-date status was compared among subjects with different SES as measured by HOUSES using a chi-square test and logistic regression models. Results: Of the 391 eligible pediatric subjects (median age of 13.1 years with male sex of 55 %), 363 (93 %) were successfully geocoded to formulate HOUSES index. HOUSES was not associated with the risk of pertussis (p = 0.82). Pertussis vaccine up-to-date statuses were 79, 86, 83, and 94 % for children in the first (the lowest SES), second, third, and fourth quartiles of HOUSES, respectively (p = 0.03). HOUSES as a continuous variable was associated with pertussis vaccine up-to-date status (adjusted OR: 1.15 per increment of one unit of HOUSES, 95 % CI: 1.04-1.27, p = 0.008). Conclusion: While HOUSES is not associated with the risk of pertussis, it predicts vaccine up-to-date status among children with different SES. HOUSES may be a useful tool for vaccine delivery research among children.
AB - Background: We recently developed HOUSES, an individual housing-based socioeconomic status (SES) measurement for health disparities research. We assessed whether HOUSES was associated with risk of pertussis and pertussis vaccine up-to-date status in children. Methods: The study utilized a previous population-based case-control study cohort assembled during the 2004-2005 pertussis outbreak. We collected data on pertussis vaccine status (up-to-date status) at the time of the index date. Using a z-score for housing value, actual square footage, and numbers of bedrooms and bathrooms, HOUSES was formulated in continuous variable and categorized into quartiles. Vaccine up-to-date status was compared among subjects with different SES as measured by HOUSES using a chi-square test and logistic regression models. Results: Of the 391 eligible pediatric subjects (median age of 13.1 years with male sex of 55 %), 363 (93 %) were successfully geocoded to formulate HOUSES index. HOUSES was not associated with the risk of pertussis (p = 0.82). Pertussis vaccine up-to-date statuses were 79, 86, 83, and 94 % for children in the first (the lowest SES), second, third, and fourth quartiles of HOUSES, respectively (p = 0.03). HOUSES as a continuous variable was associated with pertussis vaccine up-to-date status (adjusted OR: 1.15 per increment of one unit of HOUSES, 95 % CI: 1.04-1.27, p = 0.008). Conclusion: While HOUSES is not associated with the risk of pertussis, it predicts vaccine up-to-date status among children with different SES. HOUSES may be a useful tool for vaccine delivery research among children.
KW - Epidemiology
KW - Socioeconomic status
KW - Vaccination
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U2 - 10.1186/s12889-016-3673-x
DO - 10.1186/s12889-016-3673-x
M3 - Article
AN - SCOPUS:84989848923
VL - 16
JO - BMC Public Health
JF - BMC Public Health
SN - 1471-2458
IS - 1
M1 - 1000
ER -