A new scoring-system for estimating overall survival after radiotherapy of recurrent head and neck cancers

Dirk Rades, Daniel Seidl, Stefan Janssen, Samer G. Hakim, Barbara Wollenberg, Tobias Bartscht, Steven E. Schild

Research output: Contribution to journalArticle

Abstract

Background/Aim: Locoregional recurrences of head and neck cancers are often associated with a poor overall survival (OS). Outcomes may be improved with individualized treatments considering a patient’s lifespan. A specific scoring system for estimating OS prognoses is presented. Patients and Methods: In a preceding study of these 60 patients, Eastern Cooperative Oncology Group performance score (ECOG 0-1 versus 2, p=0.002) and N-stage (N0-1 versus N2, p=0.004) were identified as independent predictors of OS. Results: In the current study, the following scoring points were assigned: ECOG performance score 2=0 points, ECOG performance score 0-1=1 point, N2=0 points, N0-1=1 point. Patient scores were 0, 1 or 2 points with 3-year OS rates of 0%, 46% and 83%, respectively (p<0.0001). On multivariable analysis, differences remained significant (p<0.0001). Conclusion: This new scoring system includes three groups of patients with significantly different OS prognoses and can assist physicians when designing individualized therapy for locoregional recurrences of head and neck cancer.

Original languageEnglish (US)
Pages (from-to)1611-1613
Number of pages3
JournalAnticancer Research
Volume38
Issue number3
DOIs
StatePublished - Mar 1 2018

Keywords

  • Head
  • Locoregional recurrence
  • Neck cancer
  • Overall survival
  • Radiotherapy
  • Scoring system

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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  • Cite this

    Rades, D., Seidl, D., Janssen, S., Hakim, S. G., Wollenberg, B., Bartscht, T., & Schild, S. E. (2018). A new scoring-system for estimating overall survival after radiotherapy of recurrent head and neck cancers. Anticancer Research, 38(3), 1611-1613. https://doi.org/10.21873/anticanres.12391