A new protein that gels F actin in the cell cortex of Dictyostelium discoideum

John Coudeelis, Jeffrey L Salisbury, Keigi Fujiwara

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

It is thought that the dense actin filament networks found in the cortex of many cell types1-4 might account for the gelled consistency of the cortex5 and the exclusion of other organelles from this region of the cytoplasm6-8. We now demonstrate that a new actin-binding protein from Dictyostelium that gels actin in vitro is concentrated in the cell cortex, suggesting that this protein, in association with actin, accounts for the gel-like properties of this region of the cell.

Original languageEnglish (US)
Pages (from-to)161-162
Number of pages2
JournalNature
Volume292
Issue number5819
DOIs
StatePublished - 1981
Externally publishedYes

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Dictyostelium
Actins
Gels
Microfilament Proteins
Proteins
Actin Cytoskeleton
Organelles

ASJC Scopus subject areas

  • General

Cite this

A new protein that gels F actin in the cell cortex of Dictyostelium discoideum. / Coudeelis, John; Salisbury, Jeffrey L; Fujiwara, Keigi.

In: Nature, Vol. 292, No. 5819, 1981, p. 161-162.

Research output: Contribution to journalArticle

Coudeelis, John ; Salisbury, Jeffrey L ; Fujiwara, Keigi. / A new protein that gels F actin in the cell cortex of Dictyostelium discoideum. In: Nature. 1981 ; Vol. 292, No. 5819. pp. 161-162.
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